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199508

Sigma-Aldrich

Acridine Yellow G

Dye content 90 %

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About This Item

Formule empirique (notation de Hill):
C15H15N3 · HCl
Numéro CAS:
Poids moléculaire :
273.76
Numéro C.I. (Colour Index):
46025
Numéro CE :
Numéro MDL:
Code UNSPSC :
12171500
ID de substance PubChem :
Nomenclature NACRES :
NA.47

Forme

crystalline powder

Niveau de qualité

Composition

Dye content, 90%

Solubilité

water: 1 mg/mL, clear, yellow to orange

λmax

442 nm

ε (coefficient d'extinction)

44000 at 262-268 nm

Application(s)

diagnostic assay manufacturing
hematology
histology

Température de stockage

room temp

Chaîne SMILES 

Cl[H].Cc1cc2cc3cc(C)c(N)cc3nc2cc1N

InChI

1S/C15H15N3.ClH/c1-8-3-10-5-11-4-9(2)13(17)7-15(11)18-14(10)6-12(8)16;/h3-7H,16-17H2,1-2H3;1H

Clé InChI

BGLGAKMTYHWWKW-UHFFFAOYSA-N

Actions biochimiques/physiologiques

Acridine Yellow G (AYG) is an organic dye with photophysical properties. It is widely used in optics, medicine and photovoltaic cells. AYG has been used as a solar photocatalyst to increase biodegradability and remove ferulic acid, a target pollutant from wastewater. It retards the growth of glioblastoma via dual inhibition of epidermal growth factor receptor and protein kinase c kinases.

Pictogrammes

Health hazardExclamation mark

Mention d'avertissement

Warning

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Équipement de protection individuelle

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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Consulter la Bibliothèque de documents

M Teuber et al.
Biochimica et biophysica acta, 1506(1), 31-46 (2001-06-22)
Fluorescent DeltapH and DeltaPsi indicators have been screened for the non-invasive monitoring of bioenergetic processes in whole cells of the cyanobacterium Synechocystis sp. PCC 6803. Acridine yellow and Acridine orange proved to be the best DeltapH indicators for the investigation
G J Tangelder et al.
The American journal of physiology, 268(2 Pt 2), H909-H915 (1995-02-01)
A method is presented to assess in vivo in transparent tissues the leukocyte subtypes that roll in microvessels. In nine rabbits anesthetized with ketamine-xylazine, leukocyte nuclei were stained in situ with acridine yellow (3 mg/kg i.v. for 5 min). Intravital
Qi Qi et al.
The Journal of biological chemistry, 287(9), 6113-6127 (2012-01-05)
Amplification of the epidermal growth factor receptor (EGFR), frequently expressed as a constitutively active deletion mutant (EGFRvIII), occurs commonly in glioblastoma multiformes (GBM). However, blockade of EGFR is therapeutically disappointing for gliomas with PTEN deletion. To search for small molecules
T Pérez-Ruíz et al.
Analytical and bioanalytical chemistry, 375(5), 661-665 (2003-03-15)
A flow-injection configuration for the determination of formaldehyde is proposed. The method is based on the enhancing effect of formaldehyde on the oxidation of acridine yellow by bromate in acidic medium. The proposed procedure is simple, inexpensive, sensitive and suitable
Kęstutis Aidas et al.
The journal of physical chemistry. B, 117(7), 2069-2080 (2013-01-30)
Attempting to unravel mechanisms in optical probing of proteins, we have performed pilot calculations of two cationic chromophores-acridine yellow and proflavin-located at different binding sites within human serum albumin, including the two primary drug binding sites as well as a

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