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Merck
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06-996

Sigma-Aldrich

Anti-phospho-Kip1 (Thr187) Antibody

Upstate®, from rabbit

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

Forme d'anticorps

affinity purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

polyclonal

Produit purifié par

affinity chromatography

Espèces réactives

human, mouse, rat

Fabricant/nom de marque

Upstate®

Technique(s)

western blot: suitable

Isotype

IgG

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

phosphorylation (pThr187)

Informations sur le gène

human ... CDKN1B(1027)

Spécificité

phosphorylated Kip1

Immunogène

KLH-conjugated, synthetic peptide (C-PNAGSVEQ[pT]PKK) corresponding to amino acids 179-190 of human Kip1

Application

Anti-phospho-Kip1 (Thr187) Antibody is a high quality Rabbit Polyclonal Antibody for the detection of phospho-Kip1 (Thr187) & has been validated in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

Qualité

routinely evaluated by immunoblot on a HeLa cell RIPA lysate

Description de la cible

27kDa

Forme physique

0.2M Tris, 0.15 M NaCl, 0.1mM EDTA, 0.05% sodium azide before the addition of glycerol to 30%
Immunoaffinity Chromatography

Stockage et stabilité

1 year at -20°C

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1


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Consulter la Bibliothèque de documents

p27KIP1, an inhibitor of cyclin-dependent kinases.
Koff, A and Polyak, K
Progress in Cell Cycle Research, 1, 141-147 (1995)
Oncostatin M induces growth arrest by inhibition of Skp2, Cks1, and cyclin A expression and induced p21 expression.
Halfter, H; Friedrich, M; Resch, A; Kullmann, M; Stogbauer, F; Ringelstein, EB; Hengst, L
Cancer Research null
J Kato
Frontiers in bioscience : a journal and virtual library, 4, D787-D792 (1999-11-30)
The first gap phase (G1) in the mammalian cell cycle plays a pivotal role in determining whether or not cells are to initiate DNA replication. Progression through G1 phase and transition into S phase are positively and negatively regulated by
G Wolf
Kidney international, 56(4), 1262-1265 (1999-10-03)
There are two fundamentally different growth responses for cells comprising the nephron: hyperplasia or hypertrophy. Cells that progress through the normal cell cycle double their DNA content and eventually divide during mitosis. Those cells that hypertrophy stop the growth process
Shuichan Xu et al.
The Journal of biological chemistry, 282(21), 15462-15470 (2007-04-06)
p27, an important cell cycle regulator, blocks the G(1)/S transition in cells by binding and inhibiting Cdk2/cyclin A and Cdk2/cyclin E complexes (Cdk2/E). Ubiquitination and subsequent degradation play a critical role in regulating the levels of p27 during cell cycle

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