860516P

C16 Ceramide (d18:1/16:0)

Avanti Research^™ - A Croda Brand

• Synonyme(s) : N-palmitoyl-D-erythro-sphingosine
• Formule empirique (notation de Hill): C₃₄H₆₇NO₃
• Numéro CAS: 24696-26-2
• Poids moléculaire : 537.90
• Code UNSPSC : 12352211
• Nomenclature NACRES : NA.25

Propriétés

• Forme: powder
• Conditionnement: pkg of 1 × 10 mg (860516P-10mg); pkg of 1 × 100 mg (860516P-100mg); pkg of 1 × 25 mg (860516P-25mg); pkg of 1 × 5 mg (860516P-5mg); pkg of 1 × 50 mg (860516P-50mg)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand
• Type de lipide: sphingolipids
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: OC[C@]([H])(NC(CCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
• InChI: 1S/C34H67NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(37)32(31-36)35-34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h27,29,32-33,36-37H,3-26,28,30-31H2,1-2H3,(H,35,38)/b29-27+/t32-,33+/m0/s1
• Clé InChI: YDNKGFDKKRUKPY-TURZORIXSA-N

Description

Description générale

Ceramide comprise sphingosine and fatty acid and belongs to the sphingolipids family.

Application

C16 Ceramide (d18:1/16:0) has been used:

• as an internal standard in the chromatography with negative ion electrospray ionization coupled to tandem mass spectrometry for myocardial ceramide quantification
• as an internal standard for the ceramide quantification from rat samples using liquid chromatography-mass spectrometry
• to test its effect on mitochondrial stress response in worms

Actions biochimiques/physiologiques

C16 Ceramide levels are elevated in chronic alcohol-related liver disease (ALD). In general, ceramide inhibits mitochondrial function and insulin signaling. They are essential component of cell membrane and are involved in lipid raft formation. C16 ceramide based analog (C2-C16 CCPS) is potential anticancer agent used in chemotherapy. The levels of C16 ceramide and its ratio with other ceramides is regarded as a biomarker in predicting coronary artery disease (CAD). It interacts with the DNA-binding domain of tumor suppressor protein p53 and activates p53.

Conditionnement

5 mL Amber Glass Screw Cap Vial (860516P-100mg)

5 mL Amber Glass Screw Cap Vial (860516P-10mg)

5 mL Amber Glass Screw Cap Vial (860516P-25mg)

5 mL Amber Glass Screw Cap Vial (860516P-50mg)

5 mL Amber Glass Screw Cap Vial (860516P-5mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable