850156P

18:1 PI(3,4,5)P3

1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium salt), powder

• Synonyme(s) : 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-[phosphoinositol-3,4,5-trisphosphate] (ammonium salt); PIP3[3′,4′,5′](18:1(9Z)/18:1(9Z))
• Formule empirique (notation de Hill) : C₄₅H₉₈N₄O₂₂P₄
• Numéro CAS: 799268-57-8
• Poids moléculaire : 1171.17
• Code UNSPSC : 51191904
• Nomenclature NACRES : NA.25

Propriétés

• Essai: >99% (TLC)
• Forme: powder
• Conditionnement: pkg of 1 × 100 μg (with stopper and crimp cap (850156P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850156P-500ug))
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand 850156P
• Type de lipide: cardiolipins; phospholipids
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [H][C@@](COP(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H]1O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+].[NH4+].[NH4+]
• Clé InChI: CTYBALUTLRWYAN-CJXCTDJBSA-N

Description

Description générale

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Phosphatidylinositol is a structural phospholipid.[1] Phosphatidylinositol phosphate (PIP) is located in the plasma membrane.[2]

Application

18:1 PI(3,4,5)P3 is suitable to use in lipid stock preparation to form mixed micelles.[3] It has also been used:

• in the preparation of planar-supported lipid bilayers (SLBs)[4]
• in supplementing or enriching phagocyte membrane[5]
• in liposome preparation[6]

Actions biochimiques/physiologiques

Phosphoinositol-containing sphingolipids can induce ATPase at lower levels when compared to glycerophospholipids.[2]

Conditionnement

2 mL Amber Serum Vial with Stopper and Crimp Cap (850156P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850156P-500ug)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): No data available
• Point d'éclair (°C): No data available