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6-(2,2-Dicyanovinyl)-N-(2-hydroxyethyl)-1,2,3,4-tetrahydroquinoline

Name: 6-(2,2-Dicyanovinyl)-N-(2-hydroxyethyl)-1,2,3,4-tetrahydroquinoline
Brand: SIGMA
Price: 335 EUR

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Pack Size	SKU	Availability	Price
5 mg		Check Cart for Availability	€ 335,00

About This Item

Empirical Formula (Hill Notation):

C₁₅H₁₅N₃O

CAS Number:

142978-25-4

Molecular Weight:

253.30

UNSPSC Code:

12171500

PubChem Substance ID:

329798815

NACRES:

NA.47

MDL number:

MFCD00274418

€ 335,00

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Properties

Product Name

6-(2,2-Dicyanovinyl)-N-(2-hydroxyethyl)-1,2,3,4-tetrahydroquinoline,

assay

99.8% (HPLC)

Quality Segment

200

form

powder

color

orange

solubility

acetonitrile: 20 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

OCCN1CCCc2cc(CC(C#N)C#N)ccc12

InChI

1S/C15H17N3O/c16-10-13(11-17)8-12-3-4-15-14(9-12)2-1-5-18(15)6-7-19/h3-4,9,13,19H,1-2,5-8H2

InChI key

ANBPREOOKGEEDY-UHFFFAOYSA-N

Description

Application

Fluorescent molecular rotor

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This Item	C6206	C6331	320609
Sigma-Aldrich D5928 6-(2,2-Dicyanovinyl)-N-(2-hydroxyethyl)-1,2,3,4-tetrahydroquinoline	Sigma-Aldrich C6206 N-Carboxymethyl-6-(2,2-dicyanovinyl)-1,2,3,4-tetrahydroquinoline	Sigma-Aldrich C6331 9-Cyano-N,N,N′-triethylpyronine-N′-caproic acid N-hydroxysuccinimide ester chloride	Sigma-Aldrich 320609 2,4-Dichlorobenzenediazonium 1,5-naphthalenedisulfonate hydrate
color orange	color yellow	color very dark blue	color faint yellow
form powder	form powder	form powder	form powder
application(s) diagnostic assay manufacturing hematology histology	application(s) diagnostic assay manufacturing hematology histology	application(s) diagnostic assay manufacturing hematology histology	application(s) diagnostic assay manufacturing hematology histology
solubility acetonitrile: 20 mg/mL	solubility DMSO: 17.5 mg/mL, clear, bright yellow	solubility acetonitrile: 1 mg/mL, clear, blue	solubility -
assay 99.8% (HPLC)	assay ≥98% (HPLC)	assay ≥85% (HPLC)	assay -
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200

pictograms

GHS07

signalword

Warning

hcodes

H302 + H312 + H332,H315,H319,H335

pcodes

P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number

075H0920

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Spectrophotometric estimation of D-penicillamine in bulk and dosage forms using 2,6-dichloroquinone-4-chlorimide (DCQ).

A A Al-Majed

Journal of pharmaceutical and biomedical analysis, 21(4), 827-833 (2000-03-04)

A simple colorimetric method for the determination of D-penicillamine in pure form and pharmaceutical formulations is described. The method is based on coupling between D-penicillamine and 2,6-dichloroquinone-4-chlorimide (DCQ) in dimethylsulphoxide. The optimum conditions for the reaction were investigated and incorporated

Fluorescent molecular rotor binding to actin.

T Iio et al.

Journal of biochemistry, 113(2), 196-199 (1993-02-01)

1-(2-Hydroxyethyl)-6-[(2,2-dicyano)vinyl]-2,3,4-trihydroquinoli ne (DCQ) is a fluorescent dye and its fluorescence yield is determined by a freedom of intramolecular rotation. When DCQ was added to an actin solution, its fluorescence intensity increased as the actin molecule transformed from G-actin to F-actin.

Antibodies for fluorescent molecular rotors.

T Iwaki et al.

Biochemistry, 32(29), 7589-7592 (1993-07-27)

We have prepared monoclonal antibodies for the fluorescent molecular rotors 9-(2-carboxy-2-cyanovinyl)julolidine (CCVJ) and 9-(dicyanovinyl)julolidine (DCVJ). Mouse monoclonal antibody (IgG2b) prepared against CCVJ-conjugated bovine serum albumin strongly bound CCVJ and DCVJ. The CCVJ (or DCVJ) binding to IgG and Fab was

Global Trade Item Number

SKU	GTIN
D5928-5MG	04061831998757

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