1228530

Dronedaron -hydrochlorid

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): N-{2-Butyl-3-[4-(3-dibutylaminopropoxy)-benzoyl]-benzofuran-5-yl}-methansulfonamid -hydrochlorid
• Empirische Formel (Hill-System): C₃₁H₄₄N₂O₅S · HCl
• CAS-Nummer: 141625-93-6
• Molekulargewicht: 593.22
• NACRES: NA.24
• PubChem Substance ID: 329749687
• UNSPSC Code: 41116107
• MDL number: MFCD00914940

Eigenschaften

• grade: pharmaceutical primary standard
• API family: dronedarone
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: Cl.CCCCN(CCCC)CCCOc1ccc(cc1)C(=O)c2c(CCCC)oc3ccc(NS(C)(=O)=O)cc23
• InChI: 1S/C31H44N2O5S.ClH/c1-5-8-12-29-30(27-23-25(32-39(4,35)36)15-18-28(27)38-29)31(34)24-13-16-26(17-14-24)37-22-11-21-33(19-9-6-2)20-10-7-3;/h13-18,23,32H,5-12,19-22H2,1-4H3;1H
• InChI key: DWKVCQXJYURSIQ-UHFFFAOYSA-N
• Gene Information: human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779), HCN4(10021), KCNJ2(3759), SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Beschreibung

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dronedarone hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Dronedarone Tablets

Biochem/physiol Actions

Dronedarone is a Class III antiarrhythmic and a multi-channel blocker for atrial fibrillation.

Dronedarone is a Class III antiarrhythmic and a multi-channel blocker for atrial fibrillation. It blocks potassium, sodium, and calcium channels and also exhibits antiadrenergic properties.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• hcodes: H413
• Hazard Classifications: Aquatic Chronic 4
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable