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T9011
Trypsinogen, PMSF treated from bovine pancreas
For use as a marker in SDS-PAGE
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
1 vial | Warenkorb auf Verfügbarkeit prüfen | € 691,00 |
Über diesen Artikel
Biological source:
bovine pancreas
€ 691,00
Warenkorb auf Verfügbarkeit prüfen
Technischer Dienst
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Unterstützung erhaltenbiological source
bovine pancreas
Quality Segment
form
powder
mol wt
~24 kDa
packaging
vial of 25 mg
application(s)
detection
storage temp.
2-8°C
Application
Trypsinogen, PMSF treated from bovine pancreas has been used as a non-phosphorylated control to analyze the phospho-protein α-casein from bovine milk by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). It has also been used as a molecular weight marker standard in SDS-PAGE.
Biochem/physiol Actions
Trypsinogen is a pancreatic proteinase and exists as isoenzymes 1 and 2. It is an inactive precursor of trypsin and gets activated by the enteropeptidase found on the brush border membrane of enterocytes in the duodenum. It is also known to proteolytically activate itself. Trypsinogen activation is associated with acute pancreatitis as it causes pancreatic enzyme cascade which activates the remaining zymogens leading to autodigestion of the neighboring tissue. Hereditary pancreatitis was shown to be caused by a Arg-His substitution at residue 117 of trypsinogen causing auto-activation of trypsinogen to trypsin.
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Dieser Artikel | |||
|---|---|---|---|
| description For use as a marker in SDS-PAGE | description essentially salt-free, lyophilized powder, ≥10,000 BAEE units/mg protein (E1%/280, after activation to trypsin) | description powder, ≥7,500 BAEE units/mg solid | description Type I, ~10,000 BAEE units/mg protein |
| biological source bovine pancreas | biological source bovine pancreas | biological source - | biological source - |
| application(s) detection | application(s) - | application(s) - | application(s) - |
| form powder | form essentially salt-free, lyophilized powder | form powder | form solid |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| mol wt ~24 kDa | mol wt 23,981 Da by calculation | mol wt 23.8 kDa | mol wt 23.8 kDa |
| Quality Level 200 | Quality Level 200 | Quality Level 400 | Quality Level 200 |
Lagerklasse
11 - Combustible Solids
Was ist los?
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
PSA (Persönliche Schutzausrüstung)
Eyeshields, Gloves, type N95 (US)
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