SRP6542

FNDC5

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

• Synonym(e): Fibronectin Type III Domain-containing Protein 5, Fibronectin Type III Repeat-containing Protein 2
• UNSPSC-Code: 12352202
• NACRES: NA.32

Eigenschaften

• Rekombinant: expressed in E. coli
• Assay: ≥95% (SDS-PAGE)
• Form: lyophilized
• Mol-Gew.: ~160 kDa
• Verpackung: pkg of 10 μg
• Verunreinigungen: <0.1 EU/μg endotoxin (LAL test)
• UniProt-Hinterlegungsnummer: Q8NAU1
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... FNDC5(252995)

Beschreibung

Allgemeine Beschreibung

Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.

extracellular domain, human aa 32-152 / mouse aa 29-149 is untagged. FNDC5 extracellular domain has 100% identity between human, mouse and rat.

Physikalische Form

Lyophilized in PBS.

Rekonstituierung

Reconstitute with 100 μsterile distilled water.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable