SML2611

Bobcat339

≥98% (HPLC)

• Synonym(e): 1-([1,1′-Biphenyl]-3-yl)-4-amino-5-chloropyrimidin-2(1H)-one, 4-Amino-1-[1,1′-biphenyl]-3-yl-5-chloro-2(1H)-pyrimidinone
• Empirische Formel (Hill-System): C₁₆H₁₂ClN₃O
• CAS-Nummer: 2280037-51-4
• Molekulargewicht: 297.74
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: NC1=NC(N(C2=CC=CC(C3=CC=CC=C3)=C2)C=C1Cl)=O
• InChI: 1S/C16H12ClN3O/c17-14-10-20(16(21)19-15(14)18)13-8-4-7-12(9-13)11-5-2-1-3-6-11/h1-10H,(H2,18,19,21)
• InChIKey: QMGYGOOYCNTEQO-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

Bobcat339 is a cell penetrant, potent and selective inhibitor of TET1 and TET2 [Ten-eleven translocation methylcytosine dioxygenase (TET) 1 and 2] that reduces content of 5-hydroxymethyl-cytosine (5hmC) in cultured neurons. Bobcat339 does not inhibit DNMT3a.

cell penetrant, potent and selective inhibitor of TET1 and TET2

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable