SML1461

Kyotorphin acetate salt

≥98% (HPLC)

• Synonym(e): (2S)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid acetate salt, KTP, L-tyrosyl-L-arginine acetate salt, Tyr-Arg acetate salt, Tyrosyl-Arginine acetate salt
• Empirische Formel (Hill-System): C₁₅H₂₃N₅O₄ · xC₂H₄O₂
• CAS-Nummer: 70904-56-2
• Molekulargewicht: 337.37 (free base basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825895
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: H₂O: 20 mg/mL, clear
• storage temp.: −20°C
• SMILES string: NC(NCCC[C@@H](C(O)=O)NC([C@@H](N)CC1=CC=C(O)C=C1)=O)=N.C
• InChI: 1S/C15H23N5O4.CH4/c16-11(8-9-3-5-10(21)6-4-9)13(22)20-12(14(23)24)2-1-7-19-15(17)18;/h3-6,11-12,21H,1-2,7-8,16H2,(H,20,22)(H,23,24)(H4,17,18,19);1H4/t11-,12-;/m0./s1
• InChI key: KTMKVRFTDZZFFE-FXMYHANSSA-N

Beschreibung

Biochem/physiol Actions

Kyotorphin is a neuroactive dipeptide (Tyr-Arg) shown to have analgesic, neuroprotective, and neuromodulatory properties. It is synthesized in nerve terminals and found in the brain and in cerebro-spinal fluid (CSF). Kyotorphin indirectly stimulates opioid receptors by releasing methionine enkephalin (met-enkephalin). CSF levels are lower in patients with persistent pain and in patients with Alzheimer′s disease.

Neuroactive dipeptide

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable