SML1147

IQ-1

≥95% (HPLC)

• Synonym(e): 2-[2-(4-Acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide
• Empirische Formel (Hill-System): C₂₁H₂₂N₄O₂
• CAS-Nummer: 331001-62-8
• Molekulargewicht: 362.42
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825681
• NACRES: NA.77

Eigenschaften

• Assay: ≥95% (HPLC)
• Form: powder
• Farbe: yellow to orange
• Löslichkeit: DMSO: 10 mg/mL, clear
• Lagertemp.: −20°C
• SMILES String: CC(C1=CC=C(N=N/C(C(N)=O)=C2NC(C)(C)CC3=C/2C=CC=C3)C=C1)=O
• InChI: 1S/C21H22N4O2/c1-13(26)14-8-10-16(11-9-14)24-25-19(20(22)27)18-17-7-5-4-6-15(17)12-21(2,3)23-18/h4-11,23H,12H2,1-3H3,(H2,22,27)/b19-18+,25-24?
• InChIKey: ZXSRRUROLCGTBS-ASEVQSCHSA-N

Beschreibung

Biochem./physiol. Wirkung

IQ-1 enhances β-catenin/CBP interactions and blocks β-catenin/p300 driven transcription, which enables mouse embryonic stem cells (ESCs) to be maintained in an undifferentiated pluripotent state, allowing expansion and self-renewal of mouse ESC populations.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• P-Sätze: P264 - P270 - P301 + P312 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable