SML0377

(S)-FTY720 phosphate

≥94% (HPLC)

• Synonym(e): (+)-(S)-FTY 720 phosphate, (2S)-2-Amino-2-[2-(4-octylphenyl)ethyl]-1-(dihydrogen phosphate)-1,3-propanediol), (S)-FTY 720P
• Empirische Formel (Hill-System): C₁₉H₃₄NO₅P
• CAS-Nummer: 402616-26-6
• Molekulargewicht: 387.45
• UNSPSC-Code: 12352211

Eigenschaften

• Assay: ≥94% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to beige
• Löslichkeit: DMSO: 0.3 mg/mL, clear (warmed)
• Lagertemp.: −20°C

Beschreibung

Biochem./physiol. Wirkung

FTY20 phosphate (FTY720-P) is a sphingosine 1-phosphate (S1PR) receptor agonist and immunomodulatory agent, the active metabolite of FTY720. FTY720P acts as a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4, and S1P5), with IC₅₀ values of 0.2-6 nM.

Leistungsmerkmale und Vorteile

This compound is featured on the Lysophospholipid Receptors and Lysophospholipid Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable