SML0285

Pleuromutilin

≥95%

• Synonym(e): Drosophilin B, Mutilin 14-glycolate, NSC 121145
• Empirische Formel (Hill-System): C₂₂H₃₄O₅
• CAS-Nummer: 125-65-5
• Molekulargewicht: 378.50
• PubChem Substance ID: 329825293
• UNSPSC Code: 12352200
• NACRES: NA.77
• EC Number: 204-747-5
• Assay: ≥95%
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥95%
• form: powder
• optical activity: [α]/D +30 to +40° (c=1; CH2Cl2)
• color: white to beige
• solubility: DMSO: >10 mg/mL (warmed)
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@]1(C)[C@@H](C[C@@](C)(C=C)[C@@H](O)[C@@H]3C)OC(=O)CO
• InChI: 1S/C22H34O5/c1-6-20(4)11-16(27-17(25)12-23)21(5)13(2)7-9-22(14(3)19(20)26)10-8-15(24)18(21)22/h6,13-14,16,18-19,23,26H,1,7-12H2,2-5H3/t13-,14+,16-,18+,19+,20-,21+,22+/m1/s1
• InChI key: ZRZNJUXESFHSIO-BKUNHTPHSA-N

Beschreibung

Biochem/physiol Actions

Pleuromutilin is an antibiotic natural product that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase center and inhibiting peptide bond formation.

Pleuromutilin is an antibiotic natural product that inhibits bacterial protein synthesis.

Pleuromutilin is a diterpene that acts against gram positive bacteria and mycoplasm. It is present in Pleurotus mutilus and Pleurotus passecherianus. Pleuromutilin exhibits its antibacterial action by interfering with the prokaryotic 70S ribosomal subunit and inactivates initiation complex. Pleuromutilin is useful in treating mycoplasma infections in animals.

Sicherheitshinweise

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H302,H410
• pcodes: P264 - P270 - P273 - P301 + P312 - P391 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable