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SMB00907

Sigma-Aldrich

Nicotinamide riboside chloride

Nicotinamide riboside chloride

≥97% (HPLC), powder

Synonym(e):

Nicotinamide riboside chloride, Nicotinamide ribose chloride

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50 MG
€ 103,00
250 MG
€ 426,00

€ 103,00


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50 MG
€ 103,00
250 MG
€ 426,00

About This Item

Empirische Formel (Hill-System):
C11H15N2O5Cl
CAS-Nummer:
Molekulargewicht:
290.70
UNSPSC-Code:
12352205
NACRES:
NA.28

€ 103,00


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Biologische Quelle

milk

Qualitätsniveau

Assay

≥97% (HPLC)

Form

powder

Farbe

white to off-white

Löslichkeit

10 mg/mL, clear, colorless

Versandbedingung

wet ice

Lagertemp.

2-8°C

SMILES String

[Cl-].[n+]2(cc(ccc2)C(=O)N)[C@@H]1O[C@@H]([C@H]([C@H]1O)O)CO

InChI

1S/C11H14N2O5.ClH/c12-10(17)6-2-1-3-13(4-6)11-9(16)8(15)7(5-14)18-11;/h1-4,7-9,11,14-16H,5H2,(H-,12,17);1H/t7-,8-,9-,11-;/m1./s1

InChIKey

YABIFCKURFRPPO-IVOJBTPCSA-N

Allgemeine Beschreibung

Nicotinamide riboside is involved in nicotinate and nicotinamide metabolism. Nicotinamide riboside was originally identified as a nutrient in milk and later discovered to be a NAD(+) precursor.

Anwendung


  • Raising NAD(+) Level Stimulates Short-Chain Dehydrogenase/Reductase Proteins to Alleviate Heart Failure Independent of Mitochondrial Protein Deacetylation: This study demonstrates the potential of Nicotinamide Riboside Chloride to elevate NAD+ levels, thereby stimulating protein activity that can alleviate heart failure symptoms, highlighting its use as a cellular metabolism booster (Walker et al., 2023).

  • Acute Treatment with Nicotinamide Riboside Chloride Reduces Hippocampal Damage and Preserves the Cognitive Function of Mice with Ischemic Injury: This study investigates the neuroprotective effects of Nicotinamide Riboside Chloride, suggesting its potential in treating neurodegenerative diseases (Cheng et al., 2022).

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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