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Merck

SAB5500001

Sigma-Aldrich

Anti-beta-Actin antibody, Rabbit monoclonal

clone SP124, recombinant, expressed in proprietary host, affinity isolated antibody

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41
Konjugat:
unconjugated
application:
FACS
IHC
Klon:
SP124, monoclonal
Speziesreaktivität:
human (tested)
citations:
58
Methode(n):
flow cytometry: 1:100
immunoblotting: 1:200
immunohistochemistry: 1:200

Biologische Quelle

rabbit

Qualitätsniveau

Rekombinant

expressed in proprietary host

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

SP124, monoclonal

Speziesreaktivität

human (tested)

Speziesreaktivität (Voraussage durch Homologie)

chicken, mouse, rat, bovine, rabbit, pig, dog, hamster, frog

Methode(n)

flow cytometry: 1:100
immunoblotting: 1:200
immunohistochemistry: 1:200

Isotyp

IgG

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

2-8°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... ACTB(60)

Allgemeine Beschreibung

ACTB (actin β) gene codes for β-actin. It is a cytoskeletal housekeeping protein. It is present in the cytoplasm. This gene is located on human chromosome 7p22.1.
Beta-actin is a nonmuscle cytoskeletal protein in all human cell types and is involved in cell motility, structure, and integrity. There are six different actin isoforms in human. Antibody to beta-actin provides a specific and useful tool in studying the intracellular distribution of beta-actin and the static and dynamic aspects of the cytoskeleton.

Immunogen

Synthetic peptide near the N-terminus of human beta-Actin protein.

Anwendung

Anti-Actin-Beta antibody has been used in western blotting.

Biochem./physiol. Wirkung

β-Actin modulates cell growth, migration and the G-actin pool. Mutations in ACTB leads to pleiotropic developmental disorder.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Die Dokumentenbibliothek aufrufen

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Jiao ZY, et al.
Molecular Medicine Reports, 14(4), 2959-2966 (2016)
Guo Ying et al.
Molecular medicine reports, 12(5), 7491-7495 (2015-10-16)
The present study aimed to investigate the expression status and clinical implications of DEK in breast cancer, in order to contribute to developments in breast cancer management. DEK expression status was detected in 628 breast cancer specimens by western blot
Exosomes Derived from Squamous Head and Neck Cancer Promote Cell Survival after Ionizing Radiation
Mutschelknaus L, et al.
PLoS ONE (2016)
Xian-Lu Song et al.
Journal of Cancer, 8(13), 2501-2510 (2017-09-14)
miRNAs play critical role in the development and progression of prostate cancer. Here we studied the role of miR-618 in prostate cancer migration and invasion. miR-618 was downregulated in metastatic androgen-independent prostate cancer (AIPC), patients with low miR-618 had poor

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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