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Merck

SAB2500308

Sigma-Aldrich

Anti-DGAT2 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-DKFZp686A15125, Anti-Diacylglycerol O-acyltransferase homolog 2, Anti-GS1999full, Anti-HMFN1045

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

goat

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

canine, human, rat, mouse

Methode(n)

ELISA: suitable
flow cytometry: suitable
immunohistochemistry: suitable

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... DGAT2(84649)

Allgemeine Beschreibung

Diacylglycerol O-acyltransferase 2 (DGAT2) possesses one or two transmembrane domains and the amino- and carboxyl-terminal regions face the cytosol. The gene encoding it is localized on human chromosome 11q13.5 and has eight exons.

Immunogen

Peptide with sequence C-KLEHPTQQDIDLYH from the internal region (near the C Terminus) of the protein sequence according to NP_115953.2.

Biochem./physiol. Wirkung

Diacylglycerol O-acyltransferase 2 (DGAT2) is involved in the final step of triacylglycerol biosynthesis. It esterifies diacylglycerol to triacylglycerol. Overexpression of the protein has been associated with hepatic steatosis.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Liver fat reduction with niacin is influenced by DGAT-2 polymorphisms in hypertriglyceridemic patients.
Hu M
Journal of Lipid Research (2012)
Roles of Acyl-CoA:Diacylglycerol Acyltransferases 1 and 2 in Triacylglycerol Synthesis and Secretion in Primary Hepatocytes.
Li C
Arteriosclerosis, Thrombosis, and Vascular Biology (2015)
Expressional profiling of prostate cancer risk SNPs at 11q13.5 identifies DGAT2 as a new target gene.
Nurminen R
Genes Chromosomes Cancer (2016)
Justin Chun et al.
Journal of the American Society of Nephrology : JASN, 33(5), 889-907 (2022-03-03)
Two variants in the gene encoding apolipoprotein L1 (APOL1) that are highly associated with African ancestry are major contributors to the large racial disparity in rates of human kidney disease. We previously demonstrated that recruitment of APOL1 risk variants G1

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