PRS3969

Anti-Sumo antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(e): Anti-GAP-modifying protein 1, Anti-SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae), Anti-Ubiquitin-like protein 1, Anti-small-ubiquitin-like modifier 1
• MDL-Nummer: MFCD02096449
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: mouse, human, rat
• Methode(n): immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProt-Hinterlegungsnummer: P63165
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... SUMO1(7341)

Beschreibung

Allgemeine Beschreibung

SUMO1 (small ubiquitin-related modifier) is also called as Pic1 (inner centromere protein-related protein), Ubl1 (ubiquitin-like protein), hSmt3 (human homolog 3), or sentrin. It is located in the nucleus. SUMO1 gene is located on human chromosome 2q33.

Immunogen

a 14 amino acid peptide from near the amino-terminus of human sumo.

Biochem./physiol. Wirkung

Suppressing SUMO1 (small ubiquitin-related modifier) stops multiplication and induces apoptosis of gastric cancer SGC-7901 cells. It is essential for HCV (hepatitis C virus) replication. Deletion of SUMO1 blocks the aggregation of lipid droplets. It involves in mitochondrial fission.

Suppressing SUMO1 (small ubiquitin-related modifier) stops multiplication and induces apoptosis of gastric cancer SGC-7901 cells. It is essential for HCV (hepatitis C virus) replication. Deletion of SUMO1 blocks the aggregation of lipid droplets. It is involved in mitochondrial fission.

Verlinkung

The action of this antibody can be blocked using blocking peptide SBP3969.

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable