N1165

Pimonidazole

≥98% (HPLC),  2-nitroimidazole hypoxia marker, powder

• Synonym(e): NSC 380540, PD 126675;, Ro 03-8799;, alpha-((2-Nitroimidazol-1-yl)methyl)-1-piperidineethanol;, alpha-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol
• Empirische Formel (Hill-System): C₁₁H₁₈N₄O₃
• CAS-Nummer: 70132-50-2
• Molekulargewicht: 254.29
• UNSPSC Code: 12352200
• PubChem Substance ID: 329818508
• NACRES: NA.77
• MDL number: MFCD00867974
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Produktname: Pimonidazole, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: yellow
• solubility: DMSO: >20 mg/mL
• storage temp.: 2-8°C
• SMILES string: OC(CN1CCCCC1)Cn2ccnc2[N+]([O-])=O
• InChI: 1S/C11H18N4O3/c16-10(8-13-5-2-1-3-6-13)9-14-7-4-12-11(14)15(17)18/h4,7,10,16H,1-3,5-6,8-9H2
• InChI key: WVWOOAYQYLJEFD-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Pimonidazole is an effective and nontoxic exogenous 2-nitroimidazole hypoxia marker.

Pimonidazole is an effective and nontoxic exogenous 2-nitroimidazole hypoxia marker. Pimonidazole forms adducts with thiol groups in proteins, peptides and amino acids.

Pimonidazole possesses a nitro group at position 2 and an imidazole ring. Pimonidazole undergoes reduction and is activated in hypoxic cells.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable