MAK530

Alkaline Phosphatase (ALP) Assay Kit

sufficient for 100 fluorometric tests

• Synonym(e): Fluorometric Alkaline Phosphatase Assay Kit
• UNSPSC-Code: 12161503
• NACRES: NA.84

Eigenschaften

• Qualitätsniveau: 100
• Anwendung(en): pharmaceutical
• Nachweisverfahren: fluorometric
• Relevante Krankheit(en): cancer; neurological disorders; gastrointestinal diseases; genitourinary disorders
• Versandbedingung: wet ice
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Alkaline phosphatase (ALP) catalyzes the hydrolysis of phosphate esters in an alkaline environment, resulting in the formation of an organic radical and inorganic phosphate. In mammals, this enzyme is found mainly in the liver and bones. Marked increase in serum ALP levels, a disease known as hyperalkalinephosphatasemia, has been associated with malignant biliary obstruction, primary biliary cirrhosis, primary sclerosing cholangitis, hepatic lymphoma and sarcoidosis.

Leistungsmerkmale und Vorteile

• Detection limit of 0.02 U/L
• Compatible with high-throughput handling systems.

Eignung

The kit is suitable for ALP activity in serum, plasma and other sources, characterization and quality control for ALP production, and for high-throughput screening for ALP modulators.

Prinzip

The Alkaline Phosphatase (ALP) Assay Kit utilizes 4-methylumbelliferyl phosphate that is hydrolyzed by ALP into the highly fluorescent product 4methylumbelliferone. The rate of the fluorescence increase is directly proportional to the enzyme activity.

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H318
• P-Sätze: P280 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Dam. 1
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1