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M4154
β-N-Methylamino-L-alanine hydrochloride
Synonym(e):
L-BMAA
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About This Item
Empirische Formel (Hill-System):
C4H10N2O2 · HCl
CAS-Nummer:
Molekulargewicht:
154.60
MDL-Nummer:
UNSPSC-Code:
12352200
Empfohlene Produkte
Lagertemp.
2-8°C
SMILES String
CNCC(N)C(O)=O
Biochem./physiol. Wirkung
Neuroexcitotoxic amino acid; may be involved in Guam amyotrophic lateral sclerosis
Lagerklassenschlüssel
13 - Non Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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András Guseo
Orvosi hetilap, 153(52), 2060-2069 (2012-12-25)
Parkinson's disease is one of the most frequent progressive degenerative disorders with unknown origin of the nervous system. The commutation of the disease on Guam led to the discovery of a neurotoxin which was also found in other continents. This
Elijah W Stommel et al.
Medical hypotheses, 80(2), 142-145 (2012-12-19)
Sporadic amyotrophic lateral sclerosis (sALS) is a fatal neurodegenerative disease with no known cause. There are many clues to suggest an environmental trigger for the disease, including reports of conjugal couples and co-localized employees that developed sALS. On the island
Travis Rush et al.
Neuroreport, 23(4), 216-219 (2012-02-09)
Determination of the environmental factors involved in neurodegenerative diseases has been elusive. Methylmercury and β-N-methylamino-L-alanine (BMAA) have both been implicated in this role. Exposure of primary cortical cultures to these compounds independently induced concentration-dependent neurotoxicity. Importantly, concentrations of BMAA (10-100
Steven A Cohen
The Analyst, 137(9), 1991-2005 (2012-03-17)
The non-protein amino acid L-α-amino-β-methylaminopropionic acid (BMAA) has been linked to several neurodegenerative diseases. Its presence in trace amounts in complex sample such as bacterial, plant and mammalian tissue extracts and hydrolyzates makes analysis a complicated process requiring good analytical
Valeska Contardo-Jara et al.
Ecotoxicology and environmental safety, 88, 72-78 (2012-11-28)
Four different aquatic plants, the Pteridophyte Lomariopsis lineata and the Bryophytes Fontinalis antipyretica, Riccia fluitans and Taxiphyllum barbieri, were tested for their capacity to absorb the neurotoxin β-N-Methylamino-L-alanine (BMAA) from water and thus their possible applicability in a "Green Liver
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