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M1544

Resorufin-Methylether

Synonym(e):

7-Methoxy-3H-phenoxazin-3-on, Methoxyresorufin, O7-Methylresorufin

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Über diesen Artikel

Empirische Formel (Hill-System):
C13H9NO3
CAS-Nummer:
Molekulargewicht:
227.22
UNSPSC Code:
12161501
NACRES:
NA.47
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
209529


assay

≥98.0% (HPLC)

Quality Level

form

powder

mp

≥220 °C (lit.)

solubility

dichloromethane: 0.95-1.05 mg/mL, clear, orange to very deep orange

storage temp.

2-8°C

SMILES string

COc1ccc2N=C3C=CC(=O)C=C3Oc2c1

InChI

1S/C13H9NO3/c1-16-9-3-5-11-13(7-9)17-12-6-8(15)2-4-10(12)14-11/h2-7H,1H3

InChI key

KNYYMGDYROYBRE-UHFFFAOYSA-N

Application

Resorufin methyl ether have been used as substrate in the incubation mixture, during the determination of cytochrome P4501A activities such as ethoxyresorufin O-deethylase (EROD) and methoxyresorufin O-demethylase(MROD) in liver microsomes, using high performance liquid chromatography(HPLC).

Biochem/physiol Actions

Fluorimetric substrate for cytochrome P450 linked enzymes.

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Dieser Artikel
B153246121E3763
assay

≥98.0% (HPLC)

assay

≥98% (TLC)

assay

≥95% (UV)

assay

≥98% (TLC)

solubility

dichloromethane: 0.95-1.05 mg/mL, clear, orange to very deep orange

solubility

chloroform: 9.80-10.20 mg/mL, clear, orange

solubility

DMF: soluble, DMSO: soluble, alcohols: soluble

solubility

chloroform: 9.80-10.20 mg/mL, clear, orange

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

form

powder

form

powder

form

solid

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

mp

≥220 °C (lit.)

mp

-

mp

223-225 °C (lit.)

mp

223-225 °C (lit.)


Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Artikel

Phase I biotransformation reactions increase drug compound polarity, mainly occurring in hepatic circulation.


Dissecting the insecticide-resistance- associated cytochrome P450 gene Cyp6g1.
McCart C and ffrench-Constant R H
Pest Management Science, 64(6), 639-645 (2008)
Determination of cytochrome P450 1A activities in mammalian liver microsomes by high-performance liquid chromatography with fluorescence detection
Hanioka N, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 744(2), 399-406 (2000)
Caroline McCart et al.
Pest management science, 64(6), 639-645 (2008-03-14)
The cytochrome P450 gene Cyp6g1 is overtranscribed in all field isolates of DDT-resistant Drosophila melanogaster (Meigen) and confers a fitness advantage when inherited via the female. Overtranscription is associated with the insertion of an Accord transposable element into the 5'



Global Trade Item Number

SKUGTIN
M1544-1MG04061834040859
M1544-5MG04061834040866

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