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L6512

Sigma-Aldrich

Lektin aus Helix pomatia aus Helix pomatia

biotin conjugate, lyophilized powder

Synonym(e):

Helix pomatia agglutinin, HPA

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About This Item

UNSPSC-Code:
12352202
NACRES:
NA.32

Konjugat

biotin conjugate

Form

lyophilized powder

Kennzeichnungsgrad

2-4 mol biotin per mol protein

Verunreinigungen

salt, free

Lagertemp.

−20°C

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Allgemeine Beschreibung

Lectins are carbohydrate-binding proteins, omnipresent, found in fungi, plants and animals. These oligomeric proteins are characterized by the presence of a carbohydrate recognition domain.

Anwendung

Lectin from Helix pomatia has been used to study its binding activities in Gyrodactylus derjavini parasitizing fins of Oncorhynchus mykiss.

Biochem./physiol. Wirkung

Lectin is useful in glycoconjugate characterizing, imaging and targeting. Lectin participates in host recognition and tissue adhesion. Lectins shows resistance to proteolytic degradation in vivo.
HPA has anti-A human blood group specificity and has an affinity for terminal N-acetyl-α-D-galactosaminyl residues. Conjugates are prepared from affinity purified lectin.

Hinweis zur Analyse

Where reported, agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, of a 1 mg/ml solution. This activity is the lowest concentration to agglutinate a 2% suspension of human blood group A erythrocytes after 1 hour incubation at 25 °C.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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Overview of fish immunity
Mucosal Health in Aquaculture, 3-54 (2015)
Histochemical characteristics of Gyrodactylus derjavini parasitizing the fins of rainbow trout (Oncorhynchus mykiss)
Buchmann K, et al.
Folia Parasitol (Praha), 45(4), 312-318 (1998)
PEAS AND LENTILS
Encyclopedia of food sciences and nutrition, 4433-4440 (2003)
Cédric Jäger et al.
BMC nephrology, 23(1), 178-178 (2022-05-11)
Recurrence of IgA nephropathy (IgAN) after kidney transplantation occurs in about 30% of patients. The relevance of recurrence for the long-term graft survival is expected to increase, since graft survival continues to improve. In a nested study within the Swiss
K Buchmann
Diseases of aquatic organisms, 32(3), 195-200 (1998-07-24)
A lethal effect of rainbow trout Oncorhynchus mykiss plasma containing intact complement factors on Gyrodactylus derjavini was demonstrated. It was associated with binding of complement factor C3 to certain carbohydrate-rich parasite structures. Parasites were exposed in vitro to plasma from
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