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E5139

DL-Ethionin

≥95% (TLC)

Synonym(e):

DL-2-Amino-4-(ethylthio)butyric acid

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Über diesen Artikel

Lineare Formel:
C2H5SCH2CH2CH(NH2)COOH
CAS-Nummer:
Molekulargewicht:
163.24
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
200-647-0
MDL number:
Beilstein/REAXYS Number:
1722529

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Produktname

DL-Ethionin, ≥95% (TLC)

InChI key

GGLZPLKKBSSKCX-UHFFFAOYSA-N

InChI

1S/C6H13NO2S/c1-2-10-4-3-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)

SMILES string

CCSCCC(N)C(O)=O

assay

≥95% (TLC)

form

powder

color

white to off-white

mp

269 °C

application(s)

cell analysis

storage temp.

−20°C

Quality Level

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Dieser Artikel
E126064340M9375
form

powder

form

powder

form

powder or crystals

form

powder

assay

≥95% (TLC)

assay

≥99% (TLC)

assay

≥99.0% (NT)

assay

≥98% (HPLC)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

storage temp.

-

mp

269 °C

mp

280 °C (dec.) (lit.)

mp

280 °C (dec.) (lit.)

mp

273 °C

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

color

white to off-white

color

white

color

white

color

white

Application


  • Superoxide dismutase activity as a measure of hepatic oxidative stress in cattle following ethionine administration.: This study evaluates the hepatic oxidative stress in cattle induced by ethionine administration by measuring superoxide dismutase activity. The findings suggest a significant oxidative response, highlighting the role of DL-Ethionine in studying liver oxidative mechanisms (Abd Ellah et al., 2009).

Biochem/physiol Actions

DL-Ethionine is a racemic mixture of the anti-methylation agent L-Ethionine and its enantiomer D-Ethionine. DL-Ethionine is used as a dietary supplement to accelerate cholangiocarcinogenesis in vivo. DL-Ethionine is used to induce oxidative stress in liver to study the levels and activities of anti-oxidative enzymes and compounds such as glutathione.

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signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Lagerklasse

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Janeli Viil et al.
Scientific reports, 7, 40322-40322 (2017-01-14)
Cells with slow proliferation kinetics that retain the nuclear label over long time periods-the label-retaining cells (LRCs)-represent multipotent stem cells in a number of adult tissues. Since the identity of liver LRCs (LLRCs) had remained elusive we utilized a genetic
Mami Furukawa et al.
Anticancer research, 29(10), 4047-4050 (2009-10-23)
To evaluate an involvement of LKB1 gene alteration during pancreatic carcinogenesis, mutations in the LKB1 gene in hamster pancreatic duct adenocarcinomas (PDAs) induced by N-nitrosobis(2-oxopropyl)amine (BOP) were investigated. Female Syrian golden hamsters received 30 mg/kg of BOP followed by repeated
Muneyoshi Kanai et al.
Journal of bioscience and bioengineering, 123(1), 8-14 (2016-08-28)
Sake yeasts are ideally suited for sake making, producing higher levels of ethanol, proliferating at lower temperatures, and producing greater levels of various aromatic components and nutrients than laboratory yeasts. To elucidate the mechanism underlying S-adenosylmethionine (SAM) accumulation in sake
Sabrina C Wentz et al.
The Journal of surgical research, 157(1), e87-e95 (2009-07-01)
Intrahepatic cholangiocarcinoma (ICC) incidence and mortality are increasing in the United States and worldwide. ICC etiologies involve chronic inflammation. We hypothesize that the nonsteroidal anti-inflammatory agent sulindac may prevent ICC by targeting cyclooxygenase-1 and -2 (COX-1, -2) as well as
Miku Hirane et al.
Molecular carcinogenesis, 55(11), 1573-1583 (2015-09-18)
Lysophosphatidic acid (LPA) signaling via LPA receptors (LPA1 to LPA6 ) mediates a variety of cellular functions, including cell motility. In the present study, we investigated the effects of LPA receptors on cell motile activity during multi-stage hepatocarcinogenesis in rat

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