Direkt zum Inhalt
Merck

D3648

Diamid

Diamide
1 of 1 reviewers received a sample product or took part in a promotion

Synonym(e):

1,1′-Azobis(N,N-dimethylformamid), Diazendicarbonsäure-bis-(N,N-dimethylamid), TMAD

Slide 1 of 3
Anmelden zur Ansicht der Organisations- und Vertragspreise.

Größe auswählen

1 G

€ 141,00

5 G

€ 571,00

€ 141,00

Warenkorb auf Verfügbarkeit prüfen
​
Großbestellung anfragen

Über diesen Artikel

Lineare Formel:
(CH3)2NCON=NCON(CH3)2
CAS-Nummer:
10465-78-8
Molekulargewicht:
172.19
UNSPSC Code:
12352102
NACRES:
NA.22
PubChem Substance ID:
24278365
EC Number:
233-951-7
Beilstein/REAXYS Number:
1910409
MDL number:
MFCD00008318

Wichtige Dokumente

Gesamtdokumentation anzeigen

Fortfahren mit

Technischer Dienst
Benötigen Sie Hilfe? Unser Team von erfahrenen Wissenschaftlern ist für Sie da.
Unterstützung erhalten

InChI key

VLSDXINSOMDCBK-BQYQJAHWSA-N

InChI

1S/C6H12N4O2/c1-9(2)5(11)7-8-6(12)10(3)4/h1-4H3/b8-7+

SMILES string

CN(C)C(=O)\N=N\C(=O)N(C)C

assay

≥98% (TLC)

form

powder

mp

113-115 °C

solubility

water: 19.60-21.00 mg/mL, clear to slightly hazy, orange

storage temp.

−20°C

Quality Level

200

Ähnliche Artikel vergleichen

Vollständigen Vergleich anzeigen

Unterschiede anzeigen

1 of 4

Dieser Artikel
127108T21407G115040
Diamide

Sigma-Aldrich

D3648

Diamide

N,N,N′,N′-Tetramethyl-1,4-butanediamine 98%

Sigma-Aldrich

127108

N,N,N′,N′-Tetramethyl-1,4-butanediamine

N,N,N′,N′-Tetramethyldiaminomethane 99%

Sigma-Aldrich

T21407

N,N,N′,N′-Tetramethyldiaminomethane

DMT-dG(dmf) Phosphoramidite configured for MerMade

Sigma-Aldrich

G115040

DMT-dG(dmf) Phosphoramidite

assay

≥98% (TLC)

assay

98%

assay

99%

assay

≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

form

powder

form

-

form

-

form

powder

solubility

water: 19.60-21.00 mg/mL, clear to slightly hazy, orange

solubility

-

solubility

-

solubility

-

storage temp.

−20°C

storage temp.

-

storage temp.

-

storage temp.

-10 to -25°C

mp

113-115 °C

mp

-

mp

-

mp

-

Application

Berichten zufolge kann es als thioloxidierendes Mittel dienen. Diamid wurde für die Titration der Protein-Glutathiolierung zur Unterscheidung von anderen oxidativen Proteinmodifikationen verwendet. Die Behandlung verstärkte die Protein-Glutathiolierung konzentrationsabhängig und hatte einen vergleichsweise geringen Effekt auf die Entstehung von Protein-Protein-Disulfidbindungen.[1]

Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
0000492900
0000492901
0000492900
0000492901
0000458107

Die passende Version wird nicht angezeigt?

Wenn Sie eine bestimmte Version benötigen, können Sie anhand der Lot- oder Chargennummer nach einem spezifischen Zertifikat suchen.

Suche nach COA

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Carlos A Sorgi et al.
Scientific reports, 7(1), 10981-10981 (2017-09-10)
The differentiation of resident tissue macrophages from embryonic precursors and that of inflammatory macrophages from bone marrow cells leads to macrophage heterogeneity. Further plasticity is displayed through their ability to be polarized as subtypes M1 and M2 in a cell
Yumei He et al.
Nucleic acids research, 45(1), 106-114 (2016-09-25)
We describe a Pap1-Oxs1 pathway for diamide-induced disulfide stress in Schizosaccharomyces pombe, where the nucleocytoplasmic HMG protein Oxs1 acts cooperatively with Pap1 to regulate transcription. Oxs1 and Pap1 form a complex when cells are exposed to diamide or Cd that
Bradford G Hill et al.
Biochimica et biophysica acta, 1797(2), 285-295 (2009-11-21)
Protein thiolation by glutathione is a reversible and regulated post-translational modification that is increased in response to oxidants and nitric oxide. Because many mitochondrial enzymes contain critical thiol residues, it has been hypothesized that thiolation reactions regulate cell metabolism and
Dierk-Christoph Pöther et al.
International journal of medical microbiology : IJMM, 303(3), 114-123 (2013-03-23)
Bacillithiol (Cys-GlcN-malate, BSH) serves as a major low molecular weight thiol in low GC Gram-positive bacteria including Bacillus species and a variety of Staphylococcus aureus strains. These bacteria do not produce glutathione (GSH). In this study, HPLC analyses were used
Yong Tao et al.
Insect biochemistry and molecular biology, 43(9), 820-828 (2013-06-29)
Anthranilic diamides, which include the new commercial insecticide, chlorantraniliprole, are an exciting new class of chemistry that target insect ryanodine receptors. These receptors regulate release of stored intracellular calcium and play a critical role in muscle contraction. As with insects
Alle zugehörigen Dokumente anzeigen
1 Review This action will navigate to reviews.

Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

1 Review This action will navigate to reviews.
1 of 1 reviewers received a sample product or took part in a promotion
1 out of 1 (100%) reviewers recommend this product

Reviews

Active Filters

  1. 1 Ratings-only review

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung