B019

Phenoxybenzamin -hydrochlorid

Name: Phenoxybenzamin -hydrochlorid
Brand: SIGMA
Price: 121 EUR

≥97%, powder

Synonym(e):

N-(2-Chlorethyl)-N-(1-methyl-2-phenoxyethyl)-benzylamin -hydrochlorid

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250 MG

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Empirische Formel (Hill-System):

C₁₈H₂₂ClNO · HCl

CAS-Nummer:

63-92-3

Molekulargewicht:

340.29

NACRES:

NA.77

PubChem Substance ID:

24277760

UNSPSC Code:

12352116

EC Number:

200-569-7

MDL number:

MFCD00055152

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Produktname

Phenoxybenzamin -hydrochlorid, ≥97%, powder

InChI key

VBCPVIWPDJVHAN-UHFFFAOYSA-N

InChI

1S/C18H22ClNO.ClH/c1-16(15-21-18-10-6-3-7-11-18)20(13-12-19)14-17-8-4-2-5-9-17;/h2-11,16H,12-15H2,1H3;1H

SMILES string

Cl[H].CC(COc1ccccc1)N(CCCl)Cc2ccccc2

assay

≥97%

form

powder

color

white

solubility

H₂O: slightly soluble
alcohol: soluble
propylene glycol: soluble

originator

Wellspring

storage temp.

2-8°C

Quality Level

100

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)

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Dieser Artikel	SML0667	C8417	SML0036
Sigma-Aldrich B019 Phenoxybenzamin -hydrochlorid	Sigma-Aldrich SML0667 PF-429242 dihydrochloride	Sigma-Aldrich C8417 N-(2-Chlorethyl)-N-Ethyl-2-Brombenzylamin -hydrochlorid	Sigma-Aldrich SML0036 Procarbazin -hydrochlorid
form powder	form powder	form solid	form powder
assay ≥97%	assay ≥98% (HPLC)	assay ≥98%	assay ≥98% (HPLC)
Quality Level 100	Quality Level 100	Quality Level 200	Quality Level 100
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. -	storage temp. 2-8°C
solubility H₂O: slightly soluble, propylene glycol: soluble, alcohol: soluble	solubility H₂O: 15 mg/mL, clear	solubility H₂O: 48 mg/mL, 0.1 M NaOH: 7 mg/mL, ethanol: soluble	solubility DMSO: ≥18 mg/mL
originator Wellspring	originator -	originator -	originator -

Biochem/physiol Actions

Calmodulin antagonist; α-adrenoceptor antagonist.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Wellspring. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

GHS08,GHS07

signalword

Warning

hcodes

H302,H351

pcodes

P201 - P301 + P312 + P330 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2

Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Y M Ning et al.

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The glucocorticoid receptor (GR) is a ligand-regulated transcription factor whose ability to bind hormone is thought to be dependent on association with the 90-kDa heat shock protein (hsp90). In the present study, we have generated a novel form of the

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