A1784
Aminopterin
synthetic (organic), ≥97% (TLC), dihydrofolate reductase inhibitor, powder
Synonym(e):
(S)-2-{4-[(2,4-Diaminopteridin-6-yl)-methylamino]-benzamido}-pentandisäure, 4-Amino-pteroyl-L-glutaminsäure, 4-Aminofolsäure, erythro-2-Amino-1-phenyl-1-propanol -hydrochlorid
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Produktname
Aminopterin, powder
biological source
synthetic (organic)
Quality Level
description
Purity (≥98%)
form
powder
color
light yellow to yellow-brown
solubility
2 M NaOH: 50 mg/mL (Solutions may be stored for 1-2 days at 4°C.)
ε (extinction coefficient)
24,500 at 282 nm in 0.1 M NaOH at 1 M, 25,700 at 261 nm in 0.1 M NaOH at 1 M, 8,100 at 373 nm in 0.1 M NaOH at 1 M
storage temp.
−20°C
SMILES string
Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1
InChI
1S/C19H20N8O5/c20-15-14-16(27-19(21)26-15)23-8-11(24-14)7-22-10-3-1-9(2-4-10)17(30)25-12(18(31)32)5-6-13(28)29/h1-4,8,12,22H,5-7H2,(H,25,30)(H,28,29)(H,31,32)(H4,20,21,23,26,27)/t12-/m0/s1
InChI key
TVZGACDUOSZQKY-LBPRGKRZSA-N
Gene Information
human ... FPGS(2356)
mouse ... Fpgs(14287)
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Verwandte Kategorien
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Dieser Artikel | |||
|---|---|---|---|
| form powder | form solid | form solid | form powder |
| assay ≥97% (TLC) | assay - | assay - | assay ≥98% (HPLC) |
| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level 100 |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility 2 M NaOH: 50 mg/mL (Solutions may be stored for 1-2 days at 4°C.), DMSO: soluble (Solutions may be stored for 1-2 days at 4°C.) | solubility 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1.4 mg/mL (Solutions may be stored for several days at 4 °C), boiling water: 100 mg/mL (Solutions may be stored for several days at 4 °C), 0.1 M HCl: soluble (Solutions may be stored for several days at 4 °C), methanol: soluble (Solutions may be stored for several days at 4 °C) | solubility H2O: slightly soluble 0.3 mg/mL (Solutions may be stored for several days at 4°C.), 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1.6 mg/mL (Solutions may be stored for several days at 4°C.) | solubility DMSO: 2 mg/L, clear |
| color yellow | color white | color white | color white to beige |
Biochem/physiol Actions
Features and Benefits
Other Notes
Ähnliches Produkt
signalword
Danger
Hazard Classifications
Acute Tox. 1 Oral - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2
Lagerklasse
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| A1784-100MG | 04061833020241 |
| A1784-1G | 04061833342985 |
| A1784-50MG | 04061833342992 |
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