Direkt zum Inhalt
Merck

95271

Sigma-Aldrich

Vitamin K1

BioXtra, ≥99.0% (sum of isomers, HPLC), mixture of isomers

Synonym(e):

2-Methyl-3-phytyl-1,4-naphthochinon, 3-Phytylmenadion, Phyllochinon, Vitamin K1(20)

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise

Größe auswählen

250 MG
€ 27,90
1 G
€ 78,20

€ 27,90


Voraussichtliches Versanddatum01. April 2025


Bulk-Bestellung anfordern

Größe auswählen

Ansicht ändern
250 MG
€ 27,90
1 G
€ 78,20

About This Item

Empirische Formel (Hill-System):
C31H46O2
CAS-Nummer:
Molekulargewicht:
450.70
Beilstein:
2568816
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352205
PubChem Substanz-ID:
NACRES:
NA.79

€ 27,90


Voraussichtliches Versanddatum01. April 2025


Bulk-Bestellung anfordern

Biologische Quelle

synthetic

Qualitätsniveau

Produktlinie

BioXtra

Assay

≥99.0% (sum of isomers, HPLC)

Form

viscous liquid

Verunreinigungen

≤20% cis-isomer

Glührückstand

≤0.1% (as SO4)

Farbe

light green-yellow to dark green-yellow
light yellow to dark yellow

Brechungsindex

n20/D 1.527 (lit.)

mp (Schmelzpunkt)

−20 °C (lit.)

Dichte

0.984 g/mL at 25 °C (lit.)

Kationenspuren

Al: ≤5 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤100 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤10 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

Lagertemp.

2-8°C

SMILES String

O=C(C1=CC=CC=C21)C(C)=C(C/C=C(CCC[C@@H](CCC[C@H](C)CCCC(C)C)C)\C)C2=O

InChI

1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1

InChIKey

MBWXNTAXLNYFJB-NKFFZRIASA-N

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Allgemeine Beschreibung

Vitamin K1, also known as phylloquinone, consists of naphthalenoid and phytyl groups.[1] Phylloquinone is present abundantly in photosynthetic plants and is a major dietary source.[2] It is a fat-soluble vitamin.[3]

Anwendung

<ul>
<li><strong>Nutritional strategies for musculoskeletal health:</strong> Nutritional strategies, including Vitamin K1, optimize musculoskeletal health for fall and fracture prevention beyond traditional nutrients like calcium and vitamin D (Webster et al., 2023 doi:10.1016/j.bonr.2023.101684).</li>
<li><strong>Role in coagulation and bone health:</strong> A comprehensive review highlights Vitamin K1′s role in reducing cardiovascular risks and details its biochemical interactions affecting coagulation and bone health (Zhao et al., 2024 doi:10.1017/jns.2023.106).</li>
</ul>

Biochem./physiol. Wirkung

Vitamin K1 (Phylloquinone) is a lipid soluble polycyclic aromatic ketone used as a cofactor in the formation of coagulation factors II (prothrombin), VII, IX and X; anticoagulant factors protein C and S and as a cell signaling factor.
Vitamin K1 plays a role as a cofactor in the synthesis of γ- carboxy glutamate (Gla), formation of coagulation factors II (prothrombin), VII, IX and X.[4]

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sonstige Hinweise

Review: Vitamin K and γ-carboxyglutamate biosynthesis[5]; Metabolic functions and mechanism of action[6]

Ähnliches Produkt

Produkt-Nr.
Beschreibung
Preisangaben

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves


Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

Die passende Version wird nicht angezeigt?

Wenn Sie eine bestimmte Version benötigen, können Sie anhand der Lot- oder Chargennummer nach einem spezifischen Zertifikat suchen.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Phylloquinone (vitamin K1): occurrence, biosynthesis and functions
Basset J G, et al.
Mini-Reviews in Medicinal Chemistry, 17(12), 1028-1038 (2017)
Vitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7
Schurgers L J, et al.
Blood, 109(8), 3279-3283 (2006)
L Uotila
Scandinavian journal of clinical and laboratory investigation. Supplementum, 201, 109-117 (1990-01-01)
Vitamin K functions in animal cells as the cofactor of the enzyme vitamin K-dependent carboxylase which catalyzes the post-translational formation of gamma-carboxyglutamyl (Gla) residues in specific vitamin K-dependent proteins. These proteins include four blood coagulation factors (prothrombin and Factors VII
Metabolism of vitamin K1 (phylloquinone) in man.
Barkhan P and Shearer M J
Proceedings of the Royal Society of Medicine, 70(2), 93-93 (1977)
Waldemar Seel et al.
Scientific reports, 10(1), 330-330 (2020-01-17)
Carotenoids are associated with several important biological functions as antenna pigments in photosynthesis or protectives against oxidative stress. Occasionally they were also discussed as part of the cold adaptation mechanism of bacteria. For two Staphylococcus xylosus strains we demonstrated an

Questions

  1. I buy the 250mg bottle and I was wondering about the concentration of the bottle because it arrives as a viscous liquid. It is very important to me to know about the concentration of the liquid to work with it.

    1 answer
    1. Product No. 95271 contains neat Vitamin K1 specified at ≥99.0% purity. Using the minimum specified purity, density, and molecular weight of Vitamin K1, this neat product would have a concentration of about 2.16 M at 25 °C.

      Helpful?

Reviews

No rating value

Active Filters

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.