95172

Poly(ethylenglykol)

BioUltra, 20,000

• Synonym(e): PEG
• Lineare Formel: H(OCH₂CH₂)_nOH
• CAS-Nummer: 25322-68-3
• MDL-Nummer: MFCD00081839
• UNSPSC-Code: 12352104
• PubChem Substanz-ID: 24890102
• NACRES: NA.26

Eigenschaften

• Qualitätsniveau: 200
• Produktlinie: BioUltra
• Form: flakes
• Mol-Gew.: M_r ~16000-24000
• Verunreinigungen: insoluble matter:, passes filter test; ≤0.001% peroxides (as H₂O₂):
• pH-Wert: 5.5-7.0 (25 °C, 50 mg/mL in H₂O)
• mp (Schmelzpunkt): 63-66 °C
• Löslichkeit: H₂O: 50 mg/mL at 25 °C, clear, colorless
• Anionenspuren: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• Kationenspuren: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤200 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤200 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 50 mg/mL in H₂O
• UV-Absorption: λ: 260 nm A_max: 0.15; λ: 280 nm A_max: 0.20
• SMILES String: C(CO)O
• InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
• InChIKey: LYCAIKOWRPUZTN-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Polyethylene glycol (PEG) is a polyether compound that is used as an additive in cosmetics, pharmaceuticals, and food.[1] It consists of repeated ethylene glycol units[-(CH₂CH₂O)_n].[2]

Anwendung

Poly(ethylene glycol) has been used as a non-absorbing polymer in aqueous dispersion or active gel assembly to stimulate the formation of filament bundles through depletion interaction.[3][4][5]

Biochem./physiol. Wirkung

Polyethylene glycol (PEG) is a synthetic polymer that is used as a gold standard in bioconjugation and nanomedicine to extend blood circulation time and enhance drug efficacy. PEG-conjugated drugs are considered safe for use in humans and are approved by the U.S. Food and Drug Administration (FDA). PEG has several biomedical applications, including biosensing, imaging, and tissue engineering.[6] It also repels protein adsorption and lowers the liver uptake, which helps in coating nanoparticles.[7]

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)