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Merck

48165

Sigma-Aldrich

Chitosan

highly viscous

Synonym(e):

2-Amino-2-deoxy-(1→4)-β-D-glucopyranan, Poly-(1,4-β-D-glucopyranosamin)

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About This Item

CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352201
NACRES:
NA.25

Biologische Quelle

(crab)

Form

powder

Verunreinigungen

≤1% insoluble matter

Glührückstand

≤2% (as SO4)

Verlust

≤12% loss on drying

Farbe

yellow

Viskosität

>400 mPa.s, 1 % in acetic acid(20 °C)

InChI

1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1

InChIKey

FLASNYPZGWUPSU-SICDJOISSA-N

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Allgemeine Beschreibung

Chitosan is a linear amino polysaccharide composed of approximately 20% β1,4-linked N-acetyl-D-glucosamine (GlcNAc) and approximately 80% β1,4-linked D-glucosamine (GlcN) that is prepared by the partial deacetylation of chitin in hot alkali.

Anwendung

Chitosan is a biocompatible, antibacterial, and biodegradable polyelectrolyte with a variety of industrial and biomedical applications. Its chemical properties and low toxicity make it particularly suitable as a component of drug and gene delivery systems, and for the development of biodegradable films and scaffolds for tissue engineering.

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Kyriaki G Zinoviadou et al.
Food & function, 3(3), 312-319 (2012-02-03)
Oil-in-water emulsions (10% w/w n-tetradecane) were prepared at pH = 5.7 by using, as surface active agents, electrostatically formed complexes of sodium stearoyl lactylate (SSL) at a concentration of 0.4% (w/w) and chitosan (CH) in a concentration range between 0
Rushita Shah et al.
Polymers, 11(12) (2019-12-19)
The application of polymeric biomaterial scaffolds utilizing crosslinking strategy has become an effective approach in these days. In the present study, the development and characterization of collagen-chitosan hydrogel film has been reported on using dual crosslinking agent's, i.e., tannic acid
Liming Hu et al.
Nanoscale, 5(8), 3103-3111 (2013-03-22)
Within the past few years, chitosan-based drug delivery vehicles have become some of the most attractive to be studied. In contrast to all other polysaccharides, chitosan has demonstrated its unique characteristics for drug delivery platforms, including its active primary amino
Alberto Busilacchi et al.
Carbohydrate polymers, 98(1), 665-676 (2013-08-31)
The idea of using chitosan as a functional delivery aid to support simultaneously PRP, stem cells and growth factors (GF) is associated with the intention to use morphogenic biomaterials to modulate the natural healing sequence in bone and other tissues.
Stephanie Supper et al.
Expert opinion on drug delivery, 11(2), 249-267 (2013-12-07)
Thermogelling chitosan (CS)/glycerophosphate (GP) solutions have been reported as a new type of parenteral in situ forming depot system. These free-flowing solutions at ambient temperature turn into semi-solid hydrogels after parenteral administration. Formulation parameters such as CS physico-chemical characteristics, CS/gelling

Questions

1–3 of 3 Questions  
  1. What is the degree of deacetylation of this reagent?

    1 answer
    1. The degree of acetylation should be above 75% for each lot, but the exact value will vary. For information on the degree of acetylation for a particular lot, contact the local technical service team.

      Helpful?

  2. What is the molecular weight of this chitosan (ref 48165)?

    1 answer
    1. The molecular weight for this product is not analyzed on a lot to lot basis. However, the expected range is 500,000 to 700,000 g/mol.

      Helpful?

  3. Greetings I wish to know if this chitosan is soluble or insoluble in water. I also realized that there is water-soluble chitosan. Please kindly clarify the difference. I need them to do laboratory experiments.

    1 answer
    1. This product has not been tested for it's solubility in water. However, one gram chitosan can be dissolved in a mixture of 100mL 10% acetic acid and 50mL methanol, and then precipitated from a precipitant consisted of 10mL ethanol and 90mL acetate ester. The treated chitosan should become soluble in acid-free water completely at 8.02mg/mL

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