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Merck

R0950000

Rifamycin S

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

1,4-Dideoxy-1,4-dihydro-1,4-dioxo-rifamycin

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About This Item

Empirische Formel (Hill-System):
C37H45NO12
CAS-Nummer:
Molekulargewicht:
695.75
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

rifamycin, rifampicin

Hersteller/Markenname

EDQM

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

InChI

1S/C37H45NO12/c1-16-11-10-12-17(2)36(46)38-23-15-24(40)26-27(32(23)44)31(43)21(6)34-28(26)35(45)37(8,50-34)48-14-13-25(47-9)18(3)33(49-22(7)39)20(5)30(42)19(4)29(16)41/h10-16,18-20,25,29-30,33,41-43H,1-9H3,(H,38,46)/b11-10+,14-13+,17-12-/t16-,18+,19+,20+,25-,29-,30+,33+,37-/m0/s1

InChIKey

BTVYFIMKUHNOBZ-ODRIEIDWSA-N

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Rifamycin S EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

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Analysenzertifikate (COA)

Lot/Batch Number

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Die Dokumentenbibliothek aufrufen

Micah Steffek et al.
Biochemistry, 42(41), 12067-12076 (2003-10-15)
Mycothiol is comprised of N-acetylcysteine (AcCys) amide linked to 1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside (GlcN-Ins) and is the predominant thiol found in most actinomycetes. Mycothiol S-conjugate amidase (Mca) cleaves the amide bond of mycothiol S-conjugates of a variety of alkylating agents and xenobiotics
Ming Chen et al.
The Journal of organic chemistry, 78(1), 3-8 (2012-06-19)
Syntheses of the C(15)-C(27) fragments of chaxamycins A/D, rifamycin S, and the C(12)-C(24) fragment of salinisporamycin have been accomplished in 10 steps from commercially available starting materials. Three crotylboron reagents were utilized to construct the seven contiguous stereocenters in these
Molecular structure and conformation of rifamycin S, a potent inhibitor of DNA-dependent RNA polymerase.
S K Arora et al.
The Journal of antibiotics, 45(3), 428-431 (1992-03-01)
S BouzBouz et al.
Organic letters, 3(25), 3995-3998 (2001-12-12)
[reaction: see text] An efficient, simple method has been developed for the stereocontrolled synthesis of polypropionate stereopentads in high enantio- and diastereomeric purities.
U C Banerjee
Enzyme and microbial technology, 15(12), 1037-1041 (1993-12-01)
Growing and resting cell systems of Curvularia lunata were used for the transformation of rifamycin B to rifamycin S. In the case of growing cells, rifamycin B was added at the time of inoculation and at the different phases of

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