PHR8745

Naltrexon

certified reference material, pharmaceutical secondary standard

• Synonym(e): Naltrexon, (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-morphinan-6-on
• Empirische Formel (Hill-System): C₂₀H₂₃NO₄
• CAS-Nummer: 16590-41-3
• Molekulargewicht: 341.40
• UNSPSC Code: 41116107
• NACRES: NA.24

Eigenschaften

• Quality Segment: 300
• grade: certified reference material, pharmaceutical secondary standard
• agency: traceable to EP Y0000400, traceable to USP 1453504
• CofA: current certificate can be downloaded
• packaging: pkg of 500 mg
• application(s): pharmaceutical
• storage temp.: 15-25°C
• SMILES string: N2([C@H]3[C@]4([C@@]5([C@@H](Oc6c5c(ccc6O)C3)C(=O)CC4)CC2)O)CC1CC1
• InChI: 1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1
• InChI key: DQCKKXVULJGBQN-XFWGSAIBSA-N

Beschreibung

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Naltrexone can be used as a reference standard for the determination of the analyte in goat plasma and human plasma using LC-MS/MS method.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Sicherheitshinweise

• Zielorgane: Central nervous system
• Lagerklasse: 11 - Combustible Solids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H302,H336
• Sicherheitshinweise: P261 - P264 - P271 - P301 + P312 - P304 + P340 + P312 - P403 + P233
• Hazard Classifications: Acute Tox. 4 Oral - STOT SE 3
• Was ist los?: WGK 3