PHR1400

Mometasonfuroat

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(e): Mometasonfuroat, (11β,16α)-9,21-Dichlor-17-[(2-furanylcarbonyl)-oxy]-11-hydroxy-16-methylpregna-1,4-dien-3,20-dion
• Empirische Formel (Hill-System): C₂₇H₃₀Cl₂O₆
• CAS-Nummer: 83919-23-7
• Molekulargewicht: 521.43
• MDL-Nummer: MFCD00866003
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329823374
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to BP 768; traceable to Ph. Eur. M2900000; traceable to USP 1445470
• API-Familie: mometasone
• Analysenzertifikat (CofA): current certificate can be downloaded
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-30°C
• SMILES String: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)c5ccco5)C(=O)CCl
• InChI: 1S/C27H30Cl2O6/c1-15-11-19-18-7-6-16-12-17(30)8-9-24(16,2)26(18,29)21(31)13-25(19,3)27(15,22(32)14-28)35-23(33)20-5-4-10-34-20/h4-5,8-10,12,15,18-19,21,31H,6-7,11,13-14H2,1-3H3/t15-,18+,19+,21+,24+,25+,26+,27+/m1/s1
• InChIKey: WOFMFGQZHJDGCX-ZULDAHANSA-N
• Angaben zum Gen: human ... NR3C1(2908)

Beschreibung

Allgemeine Beschreibung

Mometasone Furoate is a medication with anti-inflammatory and antipruritic properties, commonly used to treat mixed infections of the skin. It is also used as a corticosteroid for the treatment of asthma and its mode of action involves reducing the inflammation of the airways and preventing the loss of lung functions.

Anwendung

Mometasone Furoate may be used as a secondary pharma standard for the quantification of the analyte in pharmaceutical formulations using various chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Mometasonfuroat ist ein entzündungshemmendes Glucocorticoid.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAC3330 in the slot below. This is an example certificate only and may not be the lot that you receive.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H360D
• P-Sätze: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Gefahreneinstufungen: Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable