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H0800000

Homatropin -hydrobromid

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

DL-Homatropin -hydrobromid

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About This Item

Empirische Formel (Hill-System):
C16H21NO3 · HBr
CAS-Nummer:
51-56-9
Molekulargewicht:
356.25
MDL-Nummer:
MFCD00012676
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329815135
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

homatropine

Hersteller/Markenname

EDQM

mp (Schmelzpunkt)

214-217 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

Br.CN1C2CCC1CC(C2)OC(=O)C(O)c3ccccc3

InChI

1S/C16H21NO3.BrH/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11;/h2-6,12-15,18H,7-10H2,1H3;1H

InChIKey

DWSGTFTVBLXELC-UHFFFAOYSA-N

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Allgemeine Beschreibung

Homatropine hydrobromide is an anticholinergic agent and is commonly used as a mydriatic and cycloplegic drug in ophthalmology.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

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Preisangaben

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number

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Optometry (St. Louis, Mo.), 80(2), 70-75 (2009-02-04)
Bilateral, recurrent, or chronic anterior uveitis requires a diagnostic evaluation to rule out any systemic cause. An understanding of the possible etiologies and their diagnostic criteria is needed to manage these patients. Treating any systemic cause can decrease the recurrent
N George et al.
Autonomic & autacoid pharmacology, 30(3), 173-177 (2010-01-21)
This study investigated whether four anticholinergics which are not clinically used for relaxing the urinary bladder detrusor muscle inhibit the contraction of isolated caprine (goat) detrusor muscle: cyclopentolate (100 nm), homatropine (5 microm), ipratropium (500 nm) and valethamate (1 microm).
Sean M Bryant et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2(4), 156-159 (2007-12-12)
Most hospitals lack a sufficient supply of atropine to treat, simultaneously, patients poisoned with multiple organophosphorous compound (OC) or nerve agent. The presence of a ubiquitous alternate antidote would prove useful if mass poisoning occurred. Our objective was to evaluate
Colin C K Chan et al.
Clinical & experimental ophthalmology, 33(3), 296-297 (2005-06-04)
A case is reported of formation of a dense intraocular membrane following combined phacoemulsification-trabeculectomy surgery. The membrane might have originated from a loose piece of pigment epithelium or might have resulted from dense pigment deposition on a postoperative pupillary membrane.
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