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Merck

A0230000

Adenin

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

6-Amino-purin, Vitamin B4

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About This Item

Empirische Formel (Hill-System):
C5H5N5
CAS-Nummer:
Molekulargewicht:
135.13
Beilstein:
5777
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Biologische Quelle

synthetic

Qualität

pharmaceutical primary standard

Agentur

EP

API-Familie

adenine

Form

solid

Hersteller/Markenname

EDQM

Methode(n)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp (Schmelzpunkt)

>360 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

Nc1ncnc2[nH]cnc12

InChI

1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)

InChIKey

GFFGJBXGBJISGV-UHFFFAOYSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. Adenine belongs to the group of purine alkaloids widely distributed in plant products and beverages. It can be used as an internal microbial marker for the determination of microbial protein synthesis.

Anwendung

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Verpackung

Dieses Produkt wird, wie von der entsprechenden Pharmakopöe geliefert, angeboten. Die aktuellen Mengeneinheiten finden Sie im Referenzsubstanzen-Katalog der EDQM.

Sonstige Hinweise

Kann Verkaufsbeschränkungen unterliegen.

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Preisangaben

Piktogramme

Skull and crossbones

Signalwort

Danger

H-Sätze

Gefahreneinstufungen

Acute Tox. 3 Oral

Lagerklassenschlüssel

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

Lot/Batch Number

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Determination of adenine, caffeine, theophylline and theobromine by HPLC with amperometric detection
Meyer A, et al.
Fresenius Journal of Analytical Chemistry, 356(3-4), 284-287 (1996)
Simultaneous determination of adenine and guanine in ruminant bacterial pellets by ion-pair HPLC
Moral dGP, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 826(1-2), 257-260 (2005)
Michinori Matsuo et al.
Journal of molecular and cellular cardiology, 38(6), 907-916 (2005-05-25)
ATP-sensitive potassium (K(ATP)) channels are regulated by adenine nucleotides to convert changes in cellular metabolic levels into membrane excitability. Hence, elucidation of interaction of SUR and Kir6.x with adenine nucleotides is an important issue to understand the molecular mechanisms underlying
Didier Wion et al.
Nature reviews. Microbiology, 4(3), 183-192 (2006-02-21)
N(6)-methyl-adenine is found in the genomes of bacteria, archaea, protists and fungi. Most bacterial DNA adenine methyltransferases are part of restriction-modification systems. Certain groups of Proteobacteria also harbour solitary DNA adenine methyltransferases that provide signals for DNA-protein interactions. In gamma-proteobacteria
Georg Behrens et al.
AIDS patient care and STDs, 28(4), 168-175 (2014-03-26)
The once daily, single-tablet regimen (STR) combining rilpivirine (RPV), emtricitabine (FTC), and tenofovir disoproxil fumarate (TDF) provides a simplified treatment option for antiretroviral therapy (ART)-naïve patients with baseline HIV-1 RNA (BLVL) of ≤100,000 copies/mL. The aim of this analysis is

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