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Merck

46834

Supelco

Sulfameter

VETRANAL®, analytical standard

Synonym(e):

5-Methoxysulfadiazin, N1-(5-Methoxypyrimidin-2-yl)-sulfanilamid

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About This Item

Empirische Formel (Hill-System):
C11H12N4O3S
CAS-Nummer:
Molekulargewicht:
280.30
Beilstein:
621130
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Produktlinie

VETRANAL®

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

clinical testing

Format

neat

Lagertemp.

2-8°C

SMILES String

COc1cnc(NS(=O)(=O)c2ccc(N)cc2)nc1

InChI

1S/C11H12N4O3S/c1-18-9-6-13-11(14-7-9)15-19(16,17)10-4-2-8(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)

InChIKey

GPTONYMQFTZPKC-UHFFFAOYSA-N

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Allgemeine Beschreibung

Chemical structure: sulfonamide
Sulfameter is a long-acting sulfonamide, which is found to be effective on urinary and respiratory tract infections. It is often used for animal disease treatment and prevention.

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfameter may be used as a reference standard in the determination of sulfameter in water samples and natural animal casings using solid phase extraction with high-performance liquid chromatography coupled with an ultraviolet detector (SPR-HPLC-UV).

Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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Analysenzertifikate (COA)

Lot/Batch Number

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Die Dokumentenbibliothek aufrufen

Quantitative analysis of sulfonamide residues in natural animal casings by HPLC.
Sun H, et al.
Chromatographia, 66(5-6), 333-337 (2007)
Studies of sulfamethoxydiazine.
Chew HW, et al.
Clinical Pharmacology and Therapeutics, 6(3), 307-315 (1965)
Yongjun Wu et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 81(1), 544-547 (2011-07-29)
Sulfamethoxydiazine (SMD), which is often used for animal disease treatment, is harmful to human health. No SMD residue should be detected in food in some countries, such as USA and Japan. Therefore, it is significant to develop a high-throughput, high-sensitivity
J Horák et al.
Hepato-gastroenterology, 31(5), 199-200 (1984-10-01)
Two cases of severe sulfonamide liver injury are described. In one patient, fulminant liver failure developed after two days of taking sulfamethoxazole-trimethoprim. The patient was treated with resin hemoperfusion and recovered completely. Another patient became jaundiced after using sulfamethoxydiazine for
H S Kaumeier
Arzneimittel-Forschung, 30(10), 1794-1800 (1980-01-01)
It is demonstrated that the bioavailability of sulfamethoxydiazine (Durenat), taken as an example, is much better when administered simultaneously with a test meal than when given in the fasting state. Also a high-lipid meal in comparison with a high-protein or

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