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46648

Praziquantel

Name: Praziquantel
Brand: SIAL
Price: 67.3 EUR

VETRANAL^®, analytical standard

Synonym(e):

2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isochinolin-4-on

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Packungsgröße	SKU	Verfügbarkeit	Preis
250 mg		Warenkorb auf Verfügbarkeit prüfen	€ 67,30

Über diesen Artikel

Empirische Formel (Hill-System):

C₁₉H₂₄N₂O₂

CAS-Nummer:

55268-74-1

Molekulargewicht:

312.41

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329756613

EC Number:

259-559-6

Beilstein/REAXYS Number:

761557

MDL number:

MFCD00058531

€ 67,30

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Eigenschaften

grade

analytical standard

Quality Level

200

product line

VETRANAL^®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

antibiotic activity spectrum

parasites

application(s)

clinical testing

format

neat

mode of action

cell membrane | interferes

storage temp.

2-8°C

SMILES string

O=C1CN(CC2N1CCc3ccccc23)C(=O)C4CCCCC4

InChI

1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2

InChI key

FSVJFNAIGNNGKK-UHFFFAOYSA-N

Beschreibung

General description

Praziquantel (PZQ) is a pyrazino-isoquinoline compound used as a broad-spectrum anthelmintic drug against trematode and cestode infections.

Chemical structure: quinolone

Application

PZQ may be used as a reference standard for the determination for PZQ in:

Surface water samples by solid phase extraction (SPE) and ultra-high performance liquid chromatography-quadrupole linear ion trap tandem mass spectrometry (UHPLC-QqLIT-MS) equipped with electrospray ionization (ESI) source.
Plants by HPLC with triple quadrupole mass spectrometry (HPLC-ESI-QqQ-MS/MS) operating in multiple reaction monitoring (MRM) mode.
Tablet formulations by reversed phase (RP) HPLC with ultraviolet (UV) detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Dieser Artikel	PHR1391	P2670000	Y0001533
Supelco 46648 Praziquantel	Supelco PHR1391 Praziquantel	P2670000 Praziquantel	Y0001533 Praziquantel for system suitability
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) -	technique(s) -
application(s) clinical testing	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)
format neat	format neat	format neat	format neat
Quality Level 200	Quality Level 300	Quality Level -	Quality Level -
grade analytical standard	grade certified reference material, pharmaceutical secondary standard	grade pharmaceutical primary standard	grade pharmaceutical primary standard
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C

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hcodes

H412

pcodes

P273 - P501

Hazard Classifications

Aquatic Chronic 3

Lagerklasse

11 - Combustible Solids

wgk

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)

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Die Dokumentenbibliothek aufrufen

Study of praziquantel phytoremediation and transformation and its removal in constructed wetland.

Marsik P, et al.

Journal of Hazardous Materials, 323, 394-399 (2017)

Analysis of anthelmintics in surface water by ultra high performance liquid chromatography coupled to quadrupole linear ion trap tandem mass spectrometry.

Zrncic M, et al.

Chemosphere, 99, 224-232 (2014)

Accuracy of urine circulating cathodic antigen test for the diagnosis of Schistosoma mansoni in preschool-aged children before and after treatment.

Jean T Coulibaly et al.

PLoS neglected tropical diseases, 7(3), e2109-e2109 (2013-04-05)

The Kato-Katz technique is widely used for the diagnosis of Schistosoma mansoni, but shows low sensitivity in light-intensity infections. We assessed the accuracy of a commercially available point-of-care circulating cathodic antigen (POC-CCA) cassette test for the diagnosis of S. mansoni

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Global Trade Item Number

SKU	GTIN
46648-250MG	04061832357751

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