17311

D-Mannitol

tested according to Ph. Eur.

• Synonym(e): Mannitolum
• Empirische Formel (Hill-System): C₆H₁₄O₆
• CAS-Nummer: 69-65-8
• Molekulargewicht: 182.17
• UNSPSC Code: 12352201
• NACRES: NA.22
• PubChem Substance ID: 329751528
• EC Number: 200-711-8
• Beilstein/REAXYS Number: 1721898
• MDL number: MFCD00064287

Eigenschaften

• agency: tested according to Ph. Eur.
• Quality Segment: 200
• assay: ≥97%
• form: powder
• mp: 167-170 °C (lit.)
• solubility: water: soluble(lit.)
• SMILES string: OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
• InChI: 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
• InChI key: FBPFZTCFMRRESA-KVTDHHQDSA-N

Beschreibung

General description

D-Mannitol is an acyclic carbohydrate. Crystal parameters and space groups of the various polymorphic crystalline forms of mannitol have been reported. It has been proposed as an artificial sweetner. Synthesis of D-mannitol from D-glucose or D-glucose/D-fructose syrups in the presence of glucose isomerase and copper-on-silica has been proposed.

D-Mannitol (Mannite, Mannitolum), an alditol, is an sweet tasting crystalline solid. It is naturally found in manna, olives, mushrooms and celery plants. It has been synthesized from glucose, via catalytic hydrogenation reaction. It is widely used as growth supplement in bacterial cultures.

Application

D-Mannitol may be used in the preparation of the following:

• D-mannitol and L-iditol bis-epoxides, useful substrates for the synthesis of polyhydroxylated piperidines and azepanes
• chiral hydroxyl monophosphane, [(2S,3S,4S,5S)-3,4-dihydroxy-2,5-dimethyl-1-phenylphospholane][1]
• bisphospholanes, [1,2-bis[(2S,3S,4S,5S)-3,4-dihydroxy-2,5-dimethylphospholanyl]benzene] and [1,2-bis[(2S,3S,4S,5S)-2,5-diethyl-3,4-dihydroxyphospholanyl]benzene][1]

Biochem/physiol Actions

Ein Zuckeralkohol, der die Geschmacksknospen für süß anspricht. Wird für Untersuchungen zur Inhibition von Süße verwendet.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• ppe: Eyeshields, Gloves, type N95 (US)
• flash_point_f: Not applicable
• flash_point_c: Not applicable