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MABN668

Sigma-Aldrich

Anti-Ly6C Antibody, clone 6C3

clone 6C3, from rat

Synonym(e):

Lymphocyte antigen 6C2, Ly-6C2

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rat

Qualitätsniveau

100

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

6C3, monoclonal

Speziesreaktivität

mouse

Methode(n)

dot blot: suitable
flow cytometry: suitable

Isotyp

IgG2aκ

NCBI-Hinterlegungsnummer

NP_001092687

UniProt-Hinterlegungsnummer

P0CW03

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

mouse ... Ly6C1(17067)

Allgemeine Beschreibung

Lymphocyte antigen 6C2 (Ly6C) is a 131 AA long membrane protein that is linked to macrophage phenotype according to expression levels.

Immunogen

Whole cells expressing mouse Ly6C.

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Signalübertragung & Neurowissenschaft
Detect Lymphocyte antigen 6C2 using this rat monoclonal antibody, Anti-Ly6C Antibody, clone 6C3 validated for use in Flow Cytometry & Dot Blot.
Dot Blot Analysis: A representative lot from an independent laboratory detected Ly6C in bone marrow-derived monocytes expressing 6C3 (Butovsky, O., et al. (2012). J Clin Invest. 122(9):3063-3087.).

Qualität

Evaluated by Flow Cytometry in mouse spleen cells.

Flow Cytometry Analysis: 1 µg of this antibody detected Ly6C in 1X10E6 mouse spleen cells.

Zielbeschreibung

14 kDa calculated

Physikalische Form

Protein G Purified
Format: Purified
Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Zhilong Jiang et al.
Respiratory research, 18(1), 217-217 (2017-12-30)
SOCS3 (suppressor of cytokine signaling 3) is a negative regulator of JAK/STAT3 signaling pathway and participates in the regulation of lung inflammation in a mouse model with acute lung injury (ALI). However, it is not well understood how SOCS3 regulates
Oleg Butovsky et al.
Nature neuroscience, 17(1), 131-143 (2013-12-10)
Microglia are myeloid cells of the CNS that participate both in normal CNS function and in disease. We investigated the molecular signature of microglia and identified 239 genes and 8 microRNAs that were uniquely or highly expressed in microglia versus
Qin Huang et al.
PloS one, 14(11), e0225206-e0225206 (2019-11-15)
The engineered AAV-PHP.B family of adeno-associated virus efficiently delivers genes throughout the mouse central nervous system. To guide their application across disease models, and to inspire the development of translational gene therapy vectors for targeting neurological diseases in humans, we

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