GF300

Activin A Protein, Human Recombinant Animal Free

Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release.

• Synonym(e): Inhibin, Activin-A, Erythroid differentiation protein
• UNSPSC Code: 12352202
• NACRES: NA.77
• eCl@ss: 32160405
• Assay: >97% (SDS-PAGE and HPLC)

Eigenschaften

• Quality Segment: 100
• assay: >97% (SDS-PAGE and HPLC)
• manufacturer/tradename: Chemicon^®
• impurities: <0.1 μg/mg protein endotoxin (<1EU/μg)
• UniProt accession no.: P08476
• shipped in: dry ice
• storage temp.: -10 to -25°C

Beschreibung

General description

Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Activin proteins have a wide range of biological activities, including mesoderm induction, neural cell differentiation, bone remodeling, hematopoiesis and roles in reproductive physiology. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Recombinant human Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues.

Product Source: E. coli

Application

Research Category
Stem Cell Research

Research Sub Category
Growth Factors & Receptors

Biochem/physiol Actions

Cross Reactivty
Chicken, Dog, Frog, Mouse, Human and Mouse

Physical form

Product is filtered through a 0.2 micron filter before lyophilization.

Recombinant animal free human Activin A is manufactured using all non-animal reagents

Preparation Note

Store at -20°C for up to 6 months from date of receipt.

Analysis Note

Bioactivity assay: determined by its ability to inhibit the proliferation of mouse MPC-11 cells. The expected ED50 is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable