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AB15554

Sigma-Aldrich

Anti-AT2 Receptor Antibody

Chemicon®, from rabbit

Synonym(e):

Angiotensin II receptory type 2, AGTR2

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Aufgereinigt durch

affinity chromatography

Speziesreaktivität

mouse, rat

Darf nicht reagieren mit

human

Hersteller/Markenname

Chemicon®

Methode(n)

western blot: suitable

NCBI-Hinterlegungsnummer

NM_000686.4

UniProt-Hinterlegungsnummer

P50052

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... AGTR2(186)

Spezifität

Recognizes AT2 Receptor (Angiotensin II receptory type 2, AGTR2).

Immunogen

Purified peptide from the N-terminus of rat AT2 Receptor (Accession number P35351).

Anwendung

This Anti-AT2 Receptor Antibody is validated for use in WB for the detection of AT2 Receptor.
Western blot: 1:200-1:500 using ECL on rat brain and mouse MS1 cell lysate.
Dilutions should be made using a carrier protein such as BSA (1-3%).

Optimal working dilutions must be determined by the end user.

Physikalische Form

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.025% sodium azide as a preservative. Reconstitute with 50 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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H-Sätze

H412

P-Sätze

P273 - P501

Gefahreneinstufungen

Aquatic Chronic 3

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Marina C Muñoz et al.
The Journal of endocrinology, 221(2), 215-227 (2014-04-24)
The renin-angiotensin system (RAS) plays a crucial role in the regulation of physiological homeostasis and diseases such as hypertension, coronary artery disease, and chronic renal failure. In this cascade, the angiotensin-converting enzyme (ACE)/angiotensin II (Ang II)/AT1 receptor axis induces pathological
Roman Hafko et al.
PloS one, 8(7), e69234-e69234 (2013-07-11)
Commercially available angiotensin II At₂ receptor antibodies are widely employed for receptor localization and quantification, but they have not been adequately validated. In this study, we characterized three commercially available At₂ receptor antibodies: 2818-1 from Epitomics, sc-9040 from Santa Cruz
Brandon A Kemp et al.
Circulation research, 130(1), 96-111 (2021-11-20)
How signals from activated angiotensin type-2 receptors (AT2R) mediate inhibition of sodium ion (Na+) reabsorption in renal proximal tubule cells is currently unknown. Protein phosphatases including PP2A (protein phosphatase 2A) have been implicated in AT2R signaling in tissues other than
Lucinda M Hilliard Krause et al.
Clinical science (London, England : 1979), 134(7), 871-884 (2020-03-24)
Recently, we designed a group of peptides by sequential substitution of the naturally occurring α-amino acid throughout the Ang III peptide sequence with the corresponding β-amino acid. β-Amino acid substitution at the proline residue of Ang III (β-Pro7-Ang III) resulted
Francine Duchatsch et al.
Journal of the American Society of Hypertension : JASH, 12(8), 605-613 (2018-06-28)
Hypertension is one of the chronic side effects of dexamethasone (DEX) treatment; however, almost nothing is known about its acute effects. Therefore, the aim of this study was to investigate the possible mechanisms involved in blood pressure control after acute
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