662006

U0124

A useful negative control for MEK inhibitors U0125 and U0126.

• Synonym(e): U0124, 1,4-Diamino-2,3-dicyano-1,4- bis(methylthio)butadiene, 1,4-Diamino-2,3-dicyano-1,4-bis(methylthio)butadiene
• Empirische Formel (Hill-System): C₈H₁₀N₄S₂
• CAS-Nummer: 1140528-25-1
• Molekulargewicht: 226.32
• MDL number: MFCD00037313
• NACRES: NA.77
• UNSPSC Code: 12352200
• Assay: ≥95% (HPLC)
• Form: solid
• Storage condition: OK to freeze, protect from light

Eigenschaften

• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, protect from light
• color: white
• solubility: DMSO: 100 mg/mL
• shipped in: ambient
• storage temp.: −20°C

Beschreibung

General description

A useful negative control for MEK inhibitors U0125 (Cat. No. 662008) and U0126 (Cat. No. 662005). Does not inhibit MEK activity even at concentrations of 100 µM.

A useful negative control for the MEK inhibitors U0125 (Cat. No. 662008) and U0126 (Cat. No. 662005). Does not inhibit MEK even at concentrations of 100 µM.

Biochem/physiol Actions

Cell permeable: no

Primary Target
MEK1

Product does not compete with ATP.

Reversible: no

Packaging

Packaged under inert gas

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.

Other Notes

Favata, M.F., et al. 1998. J. Biol. Chem. 273, 18623.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable