The minimum Sapogenin content for this product is 20%. This information is lot-specific and reported in the Certificate of Analysis. A review of recent lots indicates a typical range of 21 - 26% Sapogenin. Please see the link below to review a lot-specific Certificate:
https://www.sigmaaldrich.com/product/mm/558255#product-documentation
558255
Saponin
A glycoside used to permeabilize cellular membranes. Exhibits hemolytic activity.
Synonym(e):
Saponin
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| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
100 g | Warenkorb auf Verfügbarkeit prüfen | Anfragen |
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Technischer Dienst
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Unterstützung erhaltenQuality Segment
description
Merck USA index - 14, 8365
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
≤10% ash
color
tan
solubility
water: soluble
shipped in
ambient
storage temp.
15-25°C
SMILES string
O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)C(=O)O)O[C@@H]3[C@@](C4[C@@](C5[C@]([C@@]6(C[C@H]([C@]7([C@H]([C@@H](C(CC7C6=CC5)(C)C)OC(=O)\C(=C/C)\C)OC(=O)C)CO)O)C)(CC4)C)(CC3)C
InChI
1S/C55H86O24/c1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(1
InChI key
AXNVHPCVMSNXNP-ZELRDNAQSA-N
General description
Ein Glycosid, das für die Permeabilisierung zellulärer Membrane verwendet wird. Zeigt hämolztische Aktivität.
Application
- Complete biosynthesis of QS-21 in engineered yeast: In diesem Artikel wird über die erfolgreiche Biosynthese von QS-21, einem starken Saponin-Adjuvans, in gentechnisch veränderter Hefe berichtet. Die Forschungsarbeiten zeigen das Potenzial für eine skalierbare und nachhaltige Produktion von QS-21 auf, das für die Entwicklung von Impfstoffen und Immuntherapien von entscheidender Bedeutung ist. (Liu et al., 2024).
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxizität: Gesundheitsschädlich (C)
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Dieser Artikel | |||
|---|---|---|---|
| description A glycoside used to permeabilize cellular membranes. Exhibits hemolytic activity. | description used as non-ionic surfactant | description Molecular Biology, used as non-ionic surfactant | description - |
| form solid | form powder | form - | form - |
| storage temp. 15-25°C | storage temp. - | storage temp. - | storage temp. - |
| solubility water: soluble | solubility water: 1 g/10 mL, clear to hazy, yellow to brown | solubility - | solubility - |
| impurities ≤10% ash | impurities ≤20% sulphated ash | impurities - | impurities - |
| Quality Level 100 | Quality Level 300 | Quality Level 200 | Quality Level 200 |
| description Merck USA index - 14, 8365 | description - | description - | description non-ionic |
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Lagerklasse
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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what % of this saponin is composed of sapogenin?
1 answer-
Helpful?
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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Hi All, please, is this product suitable to detect bone marrow cell cycle in mice? Regards, Ahmad
1 answer-
This product has not been tested for suitability to detect bone marrow cell cycle in mice. This is an application that will need to be determined by the end-user.
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