489350

L-(−)-Norepinephrine (+)-bitartrate salt monohydrate

≥97% (LC/MS), α,β-Adrenergic agonist, crystalline solid

• Synonym(e): L-(−)-Norepinephrine-(+)-bitartrate salt monohydrate, R(–)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol-(+)-tartrate, Noradrenaline
• Empirische Formel (Hill-System): C₈H₁₁NO₃ · C₄H₆O₆ · H₂O
• CAS-Nummer: 108341-18-0
• Molekulargewicht: 337.28
• MDL number: MFCD00150449
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥97% (LC/MS)
• Form: crystalline solid
• Storage condition: OK to freeze, desiccated

Eigenschaften

• Produktname: L-(–)-Norepinephrine-(+)-bitartrate, α,β-Adrenergic agonist.
• Quality Segment: 100
• description: Merck USA index - 14, 6695
• assay: ≥97% (LC/MS)
• form: crystalline solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, desiccated
• color: white
• solubility: water: 1 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: NC[C@H](O)c1cc(c(cc1)O)O.O[C@H]([C@@H](O)C(=O)O)C(=O)O.O
• InChI: 1S/C8H11NO3.C4H6O6.H2O/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10;/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10);1H2/t8-;1-,2-;/m01./s1
• InChI key: LNBCGLZYLJMGKP-LUDZCAPTSA-N

Beschreibung

General description

α,β-Adrenergic agonist. A vasoconstrictive agent that causes down-regulation of angiotensin II receptors. Oxidation sensitive.

Biochem/physiol Actions

Cell permeable: no

Primary Target
α,β-Adrenergic agonist

Product does not compete with ATP.

Reversible: no

Preparation Note

Addition of sodium bisulfite (at a final concentration of 0.1%) is necessary to prevent oxidation.

Following reconstituiton, refrigerate (4°C). Stock solutions are stable for up to 5 days at 4°C.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Yang, H., et al. 1996. Hypertension 27, 1277.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)

Sicherheitshinweise

• pictograms: GHS06
• signalword: Danger
• hcodes: H300 + H310
• pcodes: P262 - P264 - P280 - P301 + P310 - P302 + P352 + P310 - P361 + P364
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Oral
• Lagerklasse: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable