324470
E-4031
≥98% (HPLC), solid, K⁺ current inhibitor, Calbiochem®
Synonym(e):
E-4031, 4ʹ-[[1-[2-(6-Methyl-2-Pyridinyl)ethyl-4-Piperidinyl]carbonyl]methanesulfonanilid, 2HCl
Größe auswählen
| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
5 mg | Warenkorb auf Verfügbarkeit prüfen | € 458,00 |
Über diesen Artikel
Produktname
E-4031, A potent and selective inhibitor of the rapid type of inactivating inward-rectifying K+ current (IK, IR) (IC50 = 10 nM).
Quality Segment
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
color
white to off-white
solubility
DMSO: 50 mg/mL, water: 50 mg/mL
shipped in
ambient
storage temp.
−20°C
SMILES string
[S](=O)(=O)(Nc1ccc(cc1)C(=O)C2CCN(CC2)CCc3nc(ccc3)C)C
InChI
1S/C21H27N3O3S/c1-16-4-3-5-19(22-16)12-15-24-13-10-18(11-14-24)21(25)17-6-8-20(9-7-17)23-28(2,26)27/h3-9,18,23H,10-15H2,1-2H3
InChI key
SRUISGSHWFJION-UHFFFAOYSA-N
General description
Biochem/physiol Actions
Inhibitor des schnellen Typs von inaktivierendem einwärts gleichrichtenden K+-Strom
Preparation Note
Other Notes
Ono, K., et al. 2000. J. Physiol. (London)524 (Pt. 1), 51.
Xie, J.T., et al. 2000. Methods Find. Exp. Clin. Pharmacol.22, 67.
Bauer, C.K., et al. 1999. Mol. Cell Endocrinol. 148, 37.
Baskin, E.P., and Lynch, J.J. 1998. J. Pharmacol. Exp. Ther. 285, 135.
Weinsberg, F., et al. 1997. Pflugers Arch. 434, 1.
West, P.D., et al. 1997. J. Cardiovasc. Pharmacol. Ther.2, 205.
West, P.D., et al. 1996. Pharmacol. Toxicol.78, 89.
Legal Information
Disclaimer
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Dieser Artikel | |||
|---|---|---|---|
| description A potent and selective inhibitor of the rapid type of inactivating inward-rectifying K+ current (IK, IR) (IC50 = 10 nM). | description The COX-2 Inhibitor V, FK3311, also referenced under CAS 116686-15-8, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications. | description The Akt Inhibitor XII, Isozyme-Selective, Akti-2 controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. | description The mTOR Kinase Inhibitor II, WYE-354, also referenced under CAS 1062169-56-5, controls the biological activity of mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. |
| form solid | form solid | form solid | form solid |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥97% (mixture of regioisomers, HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| manufacturer/tradename Calbiochem® | manufacturer/tradename Calbiochem® | manufacturer/tradename Calbiochem® | manufacturer/tradename Calbiochem® |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C |
| solubility water: 50 mg/mL, DMSO: 50 mg/mL | solubility DMSO: 30 mg/mL, ethanol: 15 mg/mL | solubility water: 50 mg/mL, DMSO: 25 mg/mL | solubility DMSO: 50 mg/mL |
Lagerklasse
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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