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890895P

Avanti

18:1 TAP (DOTAP, MS Salt)

Avanti Research™ - A Croda Brand 890895P, powder

Synonym(e):

1,2-dioleoyl-3-trimethylammonium-propane (methyl sulfate salt)

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About This Item

Empirische Formel (Hill-System):
C43H83NO8S
CAS-Nummer:
144189-73-1
Molekulargewicht:
774.19
UNSPSC-Code:
12352211
NACRES:
NA.25

Form

powder

Verpackung

pkg of 2 × 100 mg (890895P-200mg)
pkg of 1 × 25 mg (890895P-25mg)

Hersteller/Markenname

Avanti Research™ - A Croda Brand 890895P

Lipid-Typ

cationic lipids
transfection

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

[H]C(C[N+](C)(C)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.O=S([O-])(OC)=O

InChI

1S/C42H80NO4.CH4O4S/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;1-5-6(2,3)4/h20-23,40H,6-19,24-39H2,1-5H3;1H3,(H,2,3,4)/q+1;/p-1/b22-20-,23-21-;

InChIKey

RSMRWWHFJMENJH-LQDDAWAPSA-M

Verwandte Kategorien

Biochem./physiol. Wirkung

1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) is a cationic lipid, used for in vitro and in vivo nucleic acid and protein delivery. The lipid composition and cell type affects the transfection potential of DOTAP. DOTAP mediates gene knockdown technique in hematopoietic stem cells (HSCs).

Verpackung

5 mL Clear Glass Sealed Ampule (890895P-200mg)
5 mL Clear Glass Sealed Ampule (890895P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Sabata Martino et al.
Journal of biomedicine & biotechnology, 2009, 410260-410260 (2009-06-09)
RNA interference technology is an ideal strategy to elucidate the mechanisms associated with human CD34(+) hematopoietic stem cell differentiation into dendritic cells. Simple manipulations in vitro can unequivocally yield alloreactive or tolerogenic populations, suggesting key implications of biochemical players that
Dmitri Simberg et al.
Critical reviews in therapeutic drug carrier systems, 21(4), 257-317 (2005-01-11)
Cationic lipid-mediated nucleic acid and protein delivery is becoming increasingly popular for in vitro and in vivo applications. While the chemistry of cationic lipid carriers is moving very rapidly, and more and more sophisticated molecules are being developed, it is
Bieong-Kil Kim et al.
Biochimica et biophysica acta, 1848(10 Pt A), 1996-2001 (2015-06-27)
The effects of lipid compositions on their physicochemical properties and transfection efficiencies were investigated. Four liposome formulations with different 1,2-dioleoyl-3-trimethylammoniumpropane (DOTAP) to dioleoylphosphatidylethanolamine (DOPE) weight ratios were investigated, that is, weight ratios 1:0 (T1P0), 3:1 (T3P1), 1:1 (T1P1), and 1:3

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