The current specification sheet for this product has the following specification for Appearance (color): White to Dark Brown and Faint Grey to Dark Grey.
https://www.sigmaaldrich.com/specification-sheets/105/121/D7148-BULK.pdf
For compounds with primary amino (-NH2) groups like this one, the most common route of decomposition is oxidation to the amine-N-oxide. And oxidation of a relatively small percentage of the 3,4-Diaminopyridine could cause the material to darken significantly.
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D7148
3,4-Diamino-pyridin
≥98%
Synonym(e):
3,4-DAP, 4,5-Diaminopyridine, Amifampridine, DAP, Pyridine-4,5-diamine
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| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
1 g | Warenkorb auf Verfügbarkeit prüfen | € 40,20 |
5 g | Warenkorb auf Verfügbarkeit prüfen | € 121,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C5H7N3
CAS-Nummer:
Molekulargewicht:
109.13
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-220-9
Beilstein/REAXYS Number:
110232
MDL number:
Assay:
≥98%
Form:
powder
Technischer Dienst
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Unterstützung erhaltenQuality Segment
assay
≥98%
form
powder
mp
216-218 °C (lit.)
SMILES string
Nc1ccncc1N
InChI
1S/C5H7N3/c6-4-1-2-8-3-5(4)7/h1-3H,7H2,(H2,6,8)
InChI key
OYTKINVCDFNREN-UHFFFAOYSA-N
Gene Information
human ... KCNA1(3736), KCNA10(3744), KCNA2(3737), KCNA3(3738), KCNA4(3739), KCNA5(3741), KCNA6(3742), KCNA7(3743), KCNB1(3745), KCNB2(9312), KCNC1(3746), KCNC2(3747), KCNC3(3748), KCNC4(3749), KCND1(3750), KCND2(3751), KCND3(3752), KCNF1(3754), KCNG1(3755), KCNG2(26251), KCNG3(170850), KCNG4(93107), KCNH1(3756), KCNH2(3757), KCNH3(23416), KCNH4(23415), KCNH5(27133), KCNH6(81033), KCNH7(90134), KCNH8(131096), KCNQ1(3784), KCNQ2(3785), KCNQ3(3786), KCNQ4(9132), KCNQ5(56479), KCNS1(3787), KCNS2(3788), KCNS3(3790), KCNV1(27012), KCNV2(169522)
General description
3,4-Diaminopyridine, also known as Amifampridine, is a heterocyclic compounds commonly used as a building block during the used for synthesis of Imidazo[4,5-c]pyridine and Co(III) Schiff base complexes.
Application
3,4-Diaminopyridine can be used as a heterocyclic building block to prepare:
- Imidazo[4,5-c]pyridine, an important scaffold used for the preparation of CP-885316.
- 9-Azajulolidine derivatives, which are used as efficient organocatalysts for acylation and aza-Morita-Baylis-Hillman reaction.
- 2-Phenylpyrido[3,4-b]pyrazine by condensation reaction with α-methylsulfinylacetophenone in benzene/acetic acid as a solvent.
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Dieser Artikel | |||
|---|---|---|---|
| description ≥98% | description 98% | description 98% | description 98% |
| assay ≥98% | assay 98% | assay 98% | assay 98% |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| form powder | form crystals | form - | form powder |
| mp 216-218 °C (lit.) | mp 117-122 °C (lit.) | mp 143-147 °C (lit.) | mp 85-89 °C (lit.) |
| Gene Information human ... KCNA1(3736), KCNA10(3744), KCNA2(3737), KCNA3(3738), KCNA4(3739), KCNA5(3741), KCNA6(3742), KCNA7(3743), KCNB1(3745), KCNB2(9312), KCNC1(3746), KCNC2(3747), KCNC3(3748), KCNC4(3749), KCND1(3750), KCND2(3751), KCND3(3752), KCNF1(3754), KCNG1(3755), KCNG2(26251), KCNG3(170850), KCNG4(93107), KCNH1(3756), KCNH2(3757), KCNH3(23416), KCNH4(23415), KCNH5(27133), KCNH6(81033), KCNH7(90134), KCNH8(131096), KCNQ1(3784), KCNQ2(3785), KCNQ3(3786), KCNQ4(9132), KCNQ5(56479), KCNS1(3787), KCNS2(3788), KCNS3(3790), KCNV1(27012), KCNV2(169522) | Gene Information - | Gene Information - | Gene Information - |
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Eye Irrit. 2
Lagerklasse
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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試薬の色についてご質問です。 試験成績表のSpecificationの項目は、Colorless to Very Dark Brownとなっていますが、この色の差が生じる要因を教えていただくことは可能でしょうか。 購入したlotはVery Dark Browでした。他社製品の色はかなり薄い印象です。
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