This product is prepared from a porcine Type A gelatin.
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904643
Thiol functionalized gelatin
Synonym(e):
Functionalized gelatin, Gelatin thiol, Gelatin-SH• Gel-SH, SH functionalized gelatin, Thiol functionalized gelatin, Thiol gelatin, Thiolated gelatin, Gelatin / GelMA & derivatives
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
1 g | Warenkorb auf Verfügbarkeit prüfen | € 189,00 |
Über diesen Artikel
NACRES:
NA.23
UNSPSC Code:
12352105
Technischer Dienst
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Unterstützung erhaltendescription
NMR: Conforms to structure, Thiol content 150-350 μmol/g
assay
150-350 μmol/g (Free Thiol Concentration by UVVI, UV-vis)
form
powder
color
white to pale yellow
storage temp.
−20°C
Application
Gelatin has received significant attention in the biomedical field due to its inherent bioactivity. Functionalized gelatin can be cross-linked with the formation of covalent bonds into highly crosslinked structures, such as hydrogels. Recent literature suggests that radical-mediated polymerized hydrogels may not be ideal for cell and protein encapsulation due to radical-mediated damage, hindered molecular transport, or altered cell-cell/cell-material interactions. Thiol-modified gelatin can be used to form hydrogels with multifunctional norbornene or allyl crosslinkers via thiol-ene click or Michael-addition reactions.
To improve solubility in water, heat to 40°C and stir for 10-15 minutes.
Disclaimer
Material should be handled under nitrogen - air/oxygen & moisture are to be avoided.
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Dieser Artikel | |||
|---|---|---|---|
| description - | description gel strength 300 g Bloom, degree of substitution 60% | description gel strength 170-195 g Bloom, degree of substitution: 60% | description gel strength 300 (bloom), degree of substitution 80%, 0.2 μm, sterile-filtered, GelMA Type B |
| form powder | form powder | form solid | form viscous liquid |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C |
| description Thiol content 150-350 μmol/g , NMR: Conforms to structure | description - | description - | description - |
| assay 150-350 μmol/g (Free Thiol Concentration by UVVI, UV-vis) | assay - | assay - | assay - |
| color white to pale yellow | color - | color - | color colorless to pale yellow |
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Could I ask what gelatin is used for the modification? Is it typ A or type B, and is the origin bovine or porcin?
1 answer-
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What is the expected bloom number for product 904643?
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It is bloom 300.
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How should it be dissolved? I tried to make a 50g/L PBS solution and left it in an incubator at 40 degrees overnight, but it did not dissolve.
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Heat the gelatin solution to at least 50 °C while stirring continuously. The gelatin should dissolve to form a slightly hazy solution with no particulates. If the issue persists, please navigate to the link https://www.sigmaaldrich.com/techservice, and click on "Product Technical Inquiries" under the Products Section with all the required information so that a member of the Technical Service team can reach out to assist further. Thank you.
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