563048

2-Brom-6-methylanilin

95%

• Lineare Formel: Br(CH₃)C₆H₃NH₂
• CAS-Nummer: 53848-17-2
• Molekulargewicht: 186.05
• MDL-Nummer: MFCD04039885
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24880072
• NACRES: NA.22

Eigenschaften

• Assay: 95%
• Brechungsindex: n20/D 1.6030 (lit.)
• bp: 105-107 °C/205 mmHg (lit.)
• Dichte: 1.4780 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: bromo
• SMILES String: Cc1cccc(Br)c1N
• InChI: 1S/C7H8BrN/c1-5-3-2-4-6(8)7(5)9/h2-4H,9H2,1H3
• InChIKey: LDUCMSVRKKDATH-UHFFFAOYSA-N

Beschreibung

Anwendung

2-Bromo-6-methylaniline can be used as a reactant to synthesize:

• Alkyl substituted bromoindazole building blocks by Pd-catalyzed Suzuki coupling reaction with various vinyl boronic acids.
• Difluoropyridoindole via Pd-catalyzed intramolecular Heck reaction with difluoropiperidinone.
• 4-Methyl-N-phenyl-1H-benzo[d]imidazol-2-amine by one-pot Cu-catalyzed domino C-N cross-coupling reaction with iodobenzene and thiourea.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 215.1 °F - closed cup
• Flammpunkt (°C): 101.7 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter