538795

2-Trifluormethyl-2-propanol

96%

• Lineare Formel: CF₃C(CH₃)₂OH
• CAS-Nummer: 507-52-8
• Molekulargewicht: 128.09
• EG-Nummer: 208-075-3
• MDL-Nummer: MFCD00014391
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24878360
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 96%
• Brechungsindex: n20/D 1.3335 (lit.)
• bp: 83 °C (lit.)
• Dichte: 1.17 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: fluoro; hydroxyl
• SMILES String: CC(C)(O)C(F)(F)F
• InChI: 1S/C4H7F3O/c1-3(2,8)4(5,6)7/h8H,1-2H3
• InChIKey: OCGWWLDZAFOHGD-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2-Trifluoromethyl-2-propanol is a fluorinated aliphatic alcohol. It can be prepared by reacting methyllithium, trifluoroacetone and trifluorovinyl bromide in ether.[1] This can also be synthesized from the reaction between methylmagnesium bromide and 1,1,1-trifluoroacetone in ether.[2]

Anwendung

2-Trifluoromethyl-2-propanol may be employed as a solvent for the preparation of [¹⁸F]fluorothymidine.[3] It may also be used in the synthesis of [2-(trifluoromethyl)-2-propyl nitrate] through nitration in nitric acid/trifluoroacetic anhydride.[4]

Sicherheitshinweise

• Piktogramme: GHS02
• Signalwort: Danger
• H-Sätze: H225
• P-Sätze: P210
• Gefahreneinstufungen: Flam. Liq. 2
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 59.0 °F - closed cup
• Flammpunkt (°C): 15 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter