464155

[3aR-[2(3′aR*,8′aS*),3′aβ,8′aβ]]-(+)-2,2′-Methylen-bis[3a,8a-dihydro-8H-inden[1,2-d]oxazol]

98%

• Empirische Formel (Hill-System): C₂₁H₁₈N₂O₂
• CAS-Nummer: 180186-94-1
• Molekulargewicht: 330.38
• NACRES: NA.22
• PubChem Substance ID: 24870145
• UNSPSC Code: 12352005
• MDL number: MFCD06797115

Eigenschaften

• Quality Segment: 200
• ligand: BOX
• assay: 98%
• optical activity: [α]22/D +353°, c = 3.7 in chloroform
• manufacturer/tradename: ECACC
• mp: 204-206 °C (lit.)
• functional group: ether
• SMILES string: C1[C@@H]2OC(CC3=N[C@H]4[C@@H](Cc5ccccc45)O3)=N[C@H]2c6ccccc16
• InChI: 1S/C21H18N2O2/c1-3-7-14-12(5-1)9-16-20(14)22-18(24-16)11-19-23-21-15-8-4-2-6-13(15)10-17(21)25-19/h1-8,16-17,20-21H,9-11H2/t16-,17-,20+,21+/m0/s1
• InChI key: BDHSVQLSNIGJNC-ZCLUNYJNSA-N

Beschreibung

Application

[3aR-[2(3′aR*,8′aS*),3′aβ,8′aβ]]-(+)-2,2′-Methylenebis[3a,8a-dihydro-8H-indeno[1,2-d]oxazole] is a C₂ symmetric chiral ligand based on bis(oxazoline) moiety, which can be used in enantioselective catalysis. It easily forms bidentate coordination complexes due to the strong affinity of the oxazoline nitrogen for various metals. Copper complex of this chiral ligand can be utilized as a reusable catalyst in the cyclopropanation reaction between styrene and ethyl diazoacetate.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H315,H319,H335
• Sicherheitshinweise: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): dust mask type N95 (US), Eyeshields, Gloves